201736-74-5Relevant academic research and scientific papers
The active site of cellobiohydrolase Cel6A from Trichoderma reesei: the roles of aspartic acids D221 and D175.
Koivula, Anu,Ruohonen, Laura,Wohlfahrt, Gerd,Reinikainen, Tapani,Teeri, Tuula T,Piens, Kathleen,Claeyssens, Marc,Weber, Martin,Vasella, Andrea,Becker, Dieter,Sinnott, Michael L,Zou, Jin-Yu,Kleywegt, Gerard J,Szardenings, Michael,Stahlberg, Jerry,Jones, T Alwyn
, p. 10015 - 10024 (2007/10/03)
Trichoderma reesei cellobiohydrolase Cel6A is an inverting glycosidase. Structural studies have established that the tunnel-shaped active site of Cel6A contains two aspartic acids, D221 and D175, that are close to the glycosidic oxygen of the scissile bon
