201804-35-5

Upstream product

• 251940-57-5 (2R/S,4R)-4-[(tert-butyldiphenylsilyl)oxy]methyl-2-hydroxytetrahydrofuran 
• 251940-56-4 (2R,4S)-4-[(tert-butyldiphenylsilyl)oxy]methyl-1,2,5-pentanetriol 
• 251940-54-2 (3S,5S)-3-[(tert-butyldiphenylsilyl)oxy]methyl-5-trityloxymethyldihydro-2(3H)-furanone 
• 251940-55-3 (2R,4S)-2-[(tert-butyldiphenylsilyl)oxy]methyl-5-trityloxy-1,4-pentanediol 

Downstream Products

• 251940-58-6 (3S,4R)-4-[(tert-butyldiphenylsilyl)oxy]methyl-3-[(1S)-1-hydroxy-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]dihydro-2(3H)-furanone 
• 251940-59-7 (3S,4R)-4-[(tert-butyldiphenylsilyl)oxy]methyl-3-[(1R)-1-hydroxy-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]dihydro-2(3H)-furanone 
• 251940-60-0 (3S,4R)-3-[(1S)-1-[(tert-butyldimethylsilyl)oxy]-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]-4-[(tert-butyldiphenylsilyl)oxy]methyldihydro-2(3H)-furanone 
• 251940-61-1 (3S,4R)-3-[(1R)-1-[(tert-butyldimethylsilyl)oxy]-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]-4-[(tert-butyldiphenylsilyl)oxy]methyldihydro-2(3H)-furanone 
• 251940-62-2 (2R,3R)-2-[(1S)-1-[(tert-butyldimethylsilyl)oxy]-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]-3-[(tert-butyldiphenylsilyl)oxy]methyl-1,4-butanediol 
• 251940-63-3 (2R,3R)-2-[(1R)-1-[(tert-butyldimethylsilyl)oxy]-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]-3-[(tert-butyldiphenylsilyl)oxy]methyl-1,4-butanediol 
• 251940-64-4 (2R,3R)-1,4-diacetoxy-2-[(1S)-1-[(tert-butyldimethylsilyl)oxy]-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]-3-[(tert-butyldiphenylsilyl)oxy]methylbutane 
• 251940-65-5 (2R,3R)-1,4-diacetoxy-2-[(1R)-1-[(tert-butyldimethylsilyl)oxy]-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]-3-[(tert-butyldiphenylsilyl)oxy]methylbutane 

Relevant academic research and scientific papers

Stereoselective synthesis of optically active methylene lactone, key intermediate for the synthesis of 1,2-oxidized furofuran lignan, from L-glutamic acid

(4R)-[(1S)-1-[(tert-Butyldimethylsilyl)oxy]-1-(2-methoxy-4,5- methylenedioxyphenyl)methyl]-3-methylenedihydro2(3H)-furanone and (4R)-[(1R)-1-[(tert-butyldimethylsilyl)-oxy]-1-(2-methoxy - 4,5 - methylenedioxyphenyl)methyl]-3-methylenedihydro-2(3H)-furanone, which are key intermediates for the synthesis of 1,2-oxidized furofuran lignan, were each stereoselectively synthesized from L-glutamic acid.