201847-52-1

Basic information

• Product Name: H-D-ALA-AMC TFA
• Synonyms: RARECHEM AH BS 0002;D-ALANINE-AMC TFA;D-ALANINE 7-AMIDO-4-METHYLCOUMARIN TRIFLUOROACETATE;D-ALANINE 7-AMIDO-4-METHYLCOUMARIN, TRIFLUOROACETATE SALT;H-D-ALA-AMC TFA;H-D-Ala-AMC;(2R)-2-Amino-N-(4-methyl-2-oxo-chromen-7-yl)propanamide;D-Ala-AMC *CAS 201847-52-1*
• CAS NO: 201847-52-1
• Molecular Formula: C15H15F3N2O5
• Molecular Weight: 360.29
• Mol File: 201847-52-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: H-D-ALA-AMC TFA(CAS DataBase Reference)
• NIST Chemistry Reference: H-D-ALA-AMC TFA(201847-52-1)
• EPA Substance Registry System: H-D-ALA-AMC TFA(201847-52-1)

Safety Data

• Hazardous Substances Data: 201847-52-1(Hazardous Substances Data)

Usage

General Description

H-D-ALA-AMC TFA is a fluorescent substrate used for the detection and measurement of aminopeptidase activity. It consists of a dipeptide sequence of N-terminal D-alanine and C-terminal 7-amino-4-methylcoumarin (AMC) linked by an amide bond. The addition of trifluoroacetic acid (TFA) to the molecule helps to stabilize the active form and enhances its solubility in organic solvents, making it easier to handle and store. H-D-ALA-AMC TFA is commonly employed in biochemical assays to study the activity of aminopeptidases and to screen for inhibitors or activators of these enzymes. Its fluorescent properties facilitate the monitoring of enzymatic reactions and the quantification of enzyme activity, making it a valuable tool in biomedical research and drug discovery.