201849-63-0

Upstream product

• 201849-62-9 (3E,7E)-9-(tert-Butyl-dimethyl-silanyloxy)-3,7-dimethyl-1-(6,6,8-trimethyl-1,4-dioxa-spiro[4.5]dec-7-en-7-yl)-nona-3,7-dien-2-ol 
• 201849-61-8 (2E,6E)-tert-butyl-(7-iodo-3-methyl-octa-2,6-dienyloxy)-dimethylsilane 
• 201849-60-7 (2E)-tert-butyl-dimethyl-(3-methyl-oct-2-en-6-ynyloxy)-silane 
• 141665-53-4 (6,6,8-Trimethyl-1,4-dioxa-spiro[4.5]dec-7-en-7-yl)-acetaldehyde 
• 201849-64-1 Acetic acid (2E,6E)-2,6-dimethyl-8-oxo-1-(2,6,6-trimethyl-5-oxo-cyclohex-1-enylmethyl)-octa-2,6-dienyl ester 

Downstream Products

• 201849-64-1 Acetic acid (2E,6E)-2,6-dimethyl-8-oxo-1-(2,6,6-trimethyl-5-oxo-cyclohex-1-enylmethyl)-octa-2,6-dienyl ester 

Relevant academic research and scientific papers

Unexpected rearrangement during biomimetic entry toward a taxane skeleton

Bicyclo[9.3.1]pentadecatriene derivative 4 which corresponds to a precursor of taxol in a biomimetic entry was constructed by means of TiCl4-Zn promoted McMurry cyclization and Mitsunobu inversion. Treatment of 4 with mercuric triflate afforded an unexpected rearrangement-transannular cyclization product 5.