201860-49-3

Basic information

• Product Name: L-TRYPTOPHAN 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE
• Synonyms: L-TRYPTOPHAN 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE;H-TRP-AMC HCL;RARECHEM AH BS 0068;H-L-Trp-AMC*HCl;H-Trp-AMC Hydrochloride salt;H-L-Trp-AMC·2HCl;L-Tryptophan-7-amido-4-methylcoumarin dihydrochloride≥ 99% (HPLC)
• CAS NO: 201860-49-3
• Molecular Formula: C21H20ClN3O3
• Molecular Weight: 397.85
• Mol File: 201860-49-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 690.1±55.0 °C(Predicted)
• Appearance: /
• Density: 1.380±0.06 g/cm3(Predicted)
• Storage Temp.: Store at 0°C
• PKA: 12.98±0.20(Predicted)
• CAS DataBase Reference: L-TRYPTOPHAN 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: L-TRYPTOPHAN 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE(201860-49-3)
• EPA Substance Registry System: L-TRYPTOPHAN 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE(201860-49-3)

Safety Data

• Hazardous Substances Data: 201860-49-3(Hazardous Substances Data)

Usage

Chemical Properties

Pale violet powder

Upstream product

• 1051376-26-1 Boc-D-Trp-4-methylcoumarin-7-ylamide 

Relevant articles and documents

Synthesis of somatostatin analogues containing C-terminal adamantane and their antiproliferative properties

On the basis of the structure of somatostatin analogue TT-232 (1), which exhibited a highly potent antitumor activity, we synthesized small linear peptide derivatives and evaluated their antitumor and apoptotic activity. Of them, Boc-Tyr-D-Trp-1-adamantylamide (5) had the most potent cell antiproliferative activity in SW480 and A431 cell lines, which was supported in A431 cell lines by FACS analysis that demonstrated a major increase in DNA fragmentation in the subG1 fraction.