201863-40-3

Upstream product

• 159722-71-1 6-[2,2-dimethyl-(4R)-1,3-dioxolan-4-yl]-2,2-dimethyl-(3aS,4R,6R,6aS)-perhydrofuro[3,4-d][1,3]dioxole-4-carbaldehyde 
• 108-86-1 bromobenzene 
• 7757-38-2 2,3,5,6-di-O-isopropylidene-D-mannofuranose 
• 144651-34-3 3,6-anhydro-1,2:4,5-di-O-isopropylidene-D-glycero-D-manno-heptitol 

Downstream Products

• 201863-44-7 Methanesulfonic acid (R)-1-[(3aS,4S,6R,6aR)-6-((R)-benzyloxy-phenyl-methyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-2-methanesulfonyloxy-ethyl ester 
• 201863-42-5 (3aR,4R,6R,6aS)-4-((R)-Benzyloxy-phenyl-methyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole 
• 201863-43-6 (R)-1-[(3aS,4R,6R,6aR)-6-((R)-Benzyloxy-phenyl-methyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-ethane-1,2-diol 
• 201863-45-8 (3aR,4R,6R,6aS)-4-((R)-Benzyloxy-phenyl-methyl)-2,2-dimethyl-6-vinyl-tetrahydro-furo[3,4-d][1,3]dioxole 
• 201863-47-0 (3aR,5S,6R,6aR)-5-((R)-Benzyloxy-phenyl-methyl)-6-hydroxy-tetrahydro-furo[3,2-b]furan-2-one 
• 201863-48-1 (2S,3S,4R,5R)-2-((R)-Benzyloxy-phenyl-methyl)-5-vinyl-tetrahydro-furan-3,4-diol 
• 201863-41-4 (R)-[(3aR,4R,6R,6aS)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-phenyl-methanol 

Relevant academic research and scientific papers

Application of PdII-catalysed oxidative cyclisation of hydroxy(vinyl)furan: Synthesis of (5R)-diastereomer of (+)-goniofufurone

A convenient synthesis of the (5R)-diastereomer of (+)-goniofufurone 5 from D-mannose has been completed. A key step is the intramolecular PdCl2-catalysed oxidative cyclisation of hydroxy(vinyl)furan 6 to lactol 16.