20188-40-3 Usage
General Description
4-AMINOMETHYL-BENZAMIDE HYDROCHLORIDE is a chemical compound with the molecular formula C8H11ClN2O. It is a hydrochloride salt form of 4-aminomethyl-benzamide, which is a benzamide derivative. 4-AMINOMETHYL-BENZAMIDE HYDROCHLORIDE is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various bioactive compounds and drugs. It is also utilized in organic synthesis and chemical research. 4-AMINOMETHYL-BENZAMIDE HYDROCHLORIDE is known for its potential therapeutic properties, including anti-inflammatory and analgesic effects, and is currently being investigated for its potential use in the treatment of various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 20188-40-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,1,8 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 20188-40:
(7*2)+(6*0)+(5*1)+(4*8)+(3*8)+(2*4)+(1*0)=83
83 % 10 = 3
So 20188-40-3 is a valid CAS Registry Number.
20188-40-3Relevant articles and documents
Switching the Selectivity of Cobalt-Catalyzed Hydrogenation of Nitriles
Dai, Huiguang,Guan, Hairong
, p. 9125 - 9130 (2018/09/21)
Previous studies of base metals for catalytic hydrogenation of nitriles to primary amines or secondary aldimines focus on designing complexes with elaborate structures. Herein, we report "twin" catalytic systems where the selectivity of nitrile hydrogenation can be tuned by including or omitting the ligand HN(CH2CH2PiPr2)2 (iPrPNHP). Simply treating CoBr2 with NaHBEt3 generates cobalt particles, which can catalyze the hydrogenation of nitriles to primary amines with high selectivity and broad functional group tolerance. Ligating CoBr2 with iPrPNHP followed by the addition of NaHBEt3, however, forms a homogeneous catalyst favoring secondary aldimines for both hydrogenation and hydrogenative coupling of benzonitrile.
