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2-AMino-6-chloroquinazolin-4-ol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

20198-17-8

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20198-17-8 Usage

Chemical classification

Heterocyclic organic compound

Components

Chlorine atom and amino group attached to a quinazoline ring

Potential applications

Antiviral and antiproliferative activities in pharmaceutical industry

Uses

Building block in synthesis of pharmaceutical drugs and agrochemicals

Valuable component

In development of new drugs and bioactive molecules

Check Digit Verification of cas no

The CAS Registry Mumber 20198-17-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,1,9 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 20198-17:
(7*2)+(6*0)+(5*1)+(4*9)+(3*8)+(2*1)+(1*7)=88
88 % 10 = 8
So 20198-17-8 is a valid CAS Registry Number.

20198-17-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Amino-6-chloro-4-quinazolinol

1.2 Other means of identification

Product number -
Other names 2-Amino-4-chloro-6-pyrimidinol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20198-17-8 SDS

20198-17-8Downstream Products

20198-17-8Relevant academic research and scientific papers

2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character

Dukat, Ma?gorzata,Alix, Katie,Worsham, Jessica,Khatri, Shailesh,Schulte, Marvin K.

, p. 5945 - 5948 (2013)

2-Amino-6-chloro-3,4-dihydroquinazoline HCl (A6CDQ, 4) binds at 5-HT 3 serotonin receptors and displays antidepressant-like action in the mouse tail suspension test (TST). Empirically, 4 was demonstrated to be a 5-HT3 receptor antagonist (two-electrode voltage clamp recordings using frog oocytes; IC50 = 0.26 μM), and one that should readily penetrate the blood-brain barrier (log P = 1.86). 5-HT3 receptor antagonists represent a potential approach to the development of new antidepressants, and 4 is an example of a structurally novel 5-HT3 receptor antagonist that is active in a preclinical antidepressant model (i.e., the mouse TST).

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