202058-00-2

Upstream product

• 202057-98-5 dimethyl 2,8-bis(methoxycarbonylmethyl)-3,7-dimethyl-5-phenyl-1,9-dipyrrylmethanedicarboxylate 
• 202057-94-1 3-Methoxycarbonylmethyl-4-methyl-1H-pyrrole-2,5-dicarboxylic acid 5-benzyl ester 2-methyl ester 
• 202057-99-6 dimethyl 2,8-bis(2-hydroxyethyl)-3,7-dimethyl-5-phenyl-1,9-dipyrrylmethanedicarboxylate 
• 202057-95-2 3-Methoxycarbonylmethyl-4-methyl-1H-pyrrole-2,5-dicarboxylic acid 2-methyl ester 
• 202057-96-3 5-Iodo-3-methoxycarbonylmethyl-4-methyl-1H-pyrrole-2-carboxylic acid methyl ester 
• 202057-97-4 3-Methoxycarbonylmethyl-4-methyl-1H-pyrrole-2-carboxylic acid methyl ester 
• 87281-59-2 4-Methoxycarbonylmethyl-3-methyl-5-trichloromethyl-1H-pyrrole-2-carboxylic acid benzyl ester 

Downstream Products

• 172269-76-0 2,8-di(2-acetoxyethyl)-3,7-dimethyl-5-phenyldipyrrylmethane-1,9-dicarboxylic acid 
• 202057-89-4 Acetic acid 2-(5-{[4-(2-acetoxy-ethyl)-5-formyl-3-methyl-1H-pyrrol-2-yl]-phenyl-methyl}-2-formyl-4-methyl-1H-pyrrol-3-yl)-ethyl ester 
• 202058-01-3 2,8-bis(2-hydroxyethyl)-3,7-dimethyl-5-phenyl-1,9-diformyldipyrrylmethane 

Relevant academic research and scientific papers

Concerning the Synthesis of 3,7,13,17-Tetramethyl-5,15-diphenylporphyrin, a Sterically Hindered Porphyrin

The synthesis of the sterically hindered porphyrin 1 (3,7,13,17-tetramethyl-5,15-diphenylporphyrin) could only be achieved by first preparing a 5,15-meso substituted octaalkylporphyrin. Thus, the synthesis of a 2,8,12,18-tetrakis(2-hydroxyethyl)-3,7,13,17-tetramethyl-5,15-diphenylporphyrin (12) had to precede the synthesis of 1. The 2-hydroxyethyl side chains were then converted into vinyl residues via the corresponding 2-chloroethyl intermediates. The four vinyl residues (at C2, C8, C12, C18) were cleaved using a resorcinol melt, and the tetra β-unsubstituted porphyrin 1 was then obtained. Porphyrin 1 could not be prepared by direct condensation of benzaldehyde with 3-methylpyrrole nor with a meso-phenyl β-unsubstituted dipyrrylmethane.