202120-60-3

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 313055-06-0 (R)-2-Amino-1-(4-fluoro-3-nitro-phenyl)-ethanol 
• 202120-59-0 Acetic acid (R)-2-acetylamino-1-(4-fluoro-3-nitro-phenyl)-ethyl ester 

Downstream Products

• 221004-71-3 (S)-2-Amino-4-methyl-pentanoic acid [(R)-2-(4-fluoro-3-nitro-phenyl)-2-hydroxy-ethyl]-amide 
• 202120-61-4 (S)-2-((S)-2-Dibenzylamino-3-hydroxy-propionylamino)-4-methyl-pentanoic acid [(R)-2-(4-fluoro-3-nitro-phenyl)-2-hydroxy-ethyl]-amide 
• 402822-41-7 (4S,7S,11R)-4-Dibenzylamino-11-hydroxy-7-isobutyl-15-nitro-2-oxa-6,9-diaza-bicyclo[10.2.2]hexadeca-1⁽¹⁵⁾,12⁽¹⁶⁾,13-triene-5,8-dione 

Relevant academic research and scientific papers

A convergent approach to cyclopeptide alkaloids: Total synthesis of sanjoinine G1

A general strategy for the synthesis of cyclopeptide alkaloids containing an endocyclic aryl-alkyl ether bond has been developed featuring a key intramolecular SNAr reaction. The importance of the N-terminal protective group in the realization

Approach towards the total synthesis of cyclopeptide alkaloids

Macrocylization via formation of aryl-alkyl ether bond was a key step in a model synthesis of 14-membered cyclopeptide alkaloids. A new chemoenzymatic synthesis of chiral 2-amino-1-arylethanol was developed in the course of this study.