202126-85-0

Basic information

• Product Name: 4-(3-FLUORO-BENZYL)-PIPERIDINE
• Synonyms: 4-(3-FLUORO-BENZYL)-PIPERIDINE;4-[(3-fluorophenyl)Methyl]piperidine
• CAS NO: 202126-85-0
• Molecular Formula: C₁₂H₁₆FN
• Molecular Weight: 193.26
• Mol File: 202126-85-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 278.583 °C at 760 mmHg
• Flash Point: 122.283 °C
• Appearance: /
• Density: 1.045 g/cm³
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(3-FLUORO-BENZYL)-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-FLUORO-BENZYL)-PIPERIDINE(202126-85-0)
• EPA Substance Registry System: 4-(3-FLUORO-BENZYL)-PIPERIDINE(202126-85-0)

Safety Data

• Hazardous Substances Data: 202126-85-0(Hazardous Substances Data)

Usage

Uses

4-(3-Fluorobenzyl)piperidine is used to prepare methylaspartate receptor antagonists with analgesic activity for neuropathic pain.

InChI:InChI=1/C12H16FN/c13-12-3-1-2-11(9-12)8-10-4-6-14-7-5-10/h1-3,9-10,14H,4-8H2

Upstream product

• 1121-86-4 1-Fluoro-3-iodobenzene 
• 159635-49-1 tert-butyl 4-methylidenepiperidine-1-carboxylate 
• 782504-42-1 (R,S)-(3-fluorophenyl)(pyridin-4-yl)methanol 
• 872-85-5 pyridine-4-carbaldehyde 
• 17318-03-5 bromo(3-fluorophenyl)magnesium 
• 1412978-66-5 benzyl 4-(3-fluorobenzylidene)piperidine-1-carboxylate 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 456-41-7 1-(Bromomethyl)-3-fluorobenzene 
• 456-42-8 m-fluorobenzyl chloride 
• 63909-57-9 3-fluoro-1-diethylphosphonomethyl-benzene 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 193203-93-9 1-benzyl-4-(3-fluorobenzylidene)piperidine 

Downstream Products

• 1412978-62-1 2-(1-ethylpiperidine-4-ylmethyl)-4-fluorobenzenesulfonyl chloride 
• 1412978-64-3 1-ethyl-4-(3-fluorobenzyl)piperidine 
• 202124-73-0 1-{2-[4-(3-fluoro-benzyl)-piperidin-1-yl]-2-oxo-ethyl}-1H-indole-5-carbonitrile 

Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders and primary brain cancer. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders and primary brain cancer.

METHODS OF TREATING LIVER DISEASES

The invention provides tricyclic compounds and their use in treating liver disorders, such as non-alcoholic steatohepatitis and related disorders (e.g., fibrosis). The compounds are contemplated to have activity against methionyl aminopeptidase 2.

NEW BENZOYL UREA DERIVATIVES

The new benzoyl urea derivatives of formula (I) wherein the meaning of X and Y independently are hydrogen atom, hydroxy, benzyloxy, amino, nitro, C1-C4 alkylsulfonamido optionally substituted with a halogen atom or halogen atoms, Cs