202132-25-0Relevant articles and documents
Dibrominative Spirocyclization of 2-Butynolyl Anilides: Synthesis of gem-Dibromospirocyclic Benzo[ d][1,3]oxazines and Their Application in the Synthesis of 4 H-Furo[3,2- b]indoles
Chaisan, Nattawadee,Ruengsangtongkul, Sureeporn,Tummatorn, Jumreang,Ruchirawat, Somsak,Chainok, Kittipong,Thongsornkleeb, Charnsak
, p. 4671 - 4698 (2021/04/06)
The combination of catalytic aqueous hydrochloric acid (HCl) and N-bromosuccinimide (NBS) generated electrophilic bromine monochloride (BrCl), which readily induced spiroannulation of 2-alkynolyl anilides (n = 1-3) to form gem-dibromospirocyclic benzo[d][
Synthesis, Biological Evaluation of ortho-Carboxamidostilbenes as Potential Inhibitors of Hyperglycemic Enzymes, and Molecular Docking Study
Abu Bakar, Mohamad Hafizi,Awang, Khalijah,Azmi, Mohamad Nurul,Che Omar, Mohammad Tasyriq,Mohamad, Norhadi,Phua, Yoong Hui,Supratman, Unang,Wahab, Habibah A.
, (2021/07/21)
A new series of ortho-carboxamidostilbenes derivatives were synthesized via Heck Coupling and screened for their α-amylase and α-glucosidase inhibitory potential. The results indicated that all the synthesized compounds showed a substantial α-glucosidase
A Pd-catalyzed domino Larock annulation/dearomative Heck reaction
Liang, Ren-Xiao,Xu, Deng-Yun,Yang, Fu-Ming,Jia, Yi-Xia
supporting information, p. 7711 - 7714 (2019/07/09)
A palladium-catalyzed domino Larock annulation/dearomative Heck reaction is developed, which delivers a range of tetracyclic indoline derivatives in moderate to excellent yields through a Larock annulation of N-bromobenzoyl o-iodoanilines with alkynes and a subsequent intramolecular dearomative Heck reaction. This protocol provides a straightforward route to structurally diverse indolines from readily available starting materials by forming two new rings and three chemical bonds in a single step.
