20218-43-3Relevant academic research and scientific papers
Monophenylation accompanied by partial reduction of 1,1-dihalogeno-2-phenyl-1-alkenes in the presence of a nickel-phosphine complex
Okamoto, Yuzo,Yoshikawa, Yutaka,Hayashi, Takatoshi
, p. 143 - 150 (1989)
Reaction of 1,1-dihalogeno-2-phenyl-1-alkenes (I) with phenylmagnesium bromide in the presence of NiCl2(dppp) in THF has been studied.Mono-cross-coupling accompanied by partial reduction gave (E)-1,2-diphenyl-1-alkenes (III) as the major products.Use of a large excess of Grignard reagent increased the yields of III and the (Z)-isomers (II), with a decrease in the yield of double cross-coupling products, 1,1,2-triphenyl-1-alkenes (IV).The highest ratio of the sum of the yields of the monophenylation products to the yield of the double cross-coupling product, (II+III)/IV=36.5, was found for the reaction of PhMgBr with 1,1-dibromo-2-phenylpropene (Ib) in a 12.0/1 molar ratio.A possible reaction mechanism is described.
Novel Coupling of Dithioacetals with Grignard Reagents
Ni, Zhi-Jie,Luh, Tien-Yau
, p. 1515 - 1517 (2007/10/02)
Dithioacetals react with Grignard reagents in the presence of a catalytic amount of to give the corresponding olefinic coupling products in good yields: a mechanism for the reaction is suggested.
