20218-43-3

Basic information

• Product Name: (E)-3-methyl-1,2-diphenyl-1-butene
• CAS NO: 20218-43-3
• Molecular Weight: 222.33
• Mol File: 20218-43-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-3-methyl-1,2-diphenyl-1-butene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-methyl-1,2-diphenyl-1-butene(20218-43-3)
• EPA Substance Registry System: (E)-3-methyl-1,2-diphenyl-1-butene(20218-43-3)

Safety Data

• Hazardous Substances Data: 20218-43-3(Hazardous Substances Data)

Upstream product

• 88142-08-9 2-benzyl-2-phenyl-1,3-dithiolane 
• 920-39-8 isopropylmagnesium bromide 
• 611-70-1 phenyl isopropyl ketone 

Relevant articles and documents

Monophenylation accompanied by partial reduction of 1,1-dihalogeno-2-phenyl-1-alkenes in the presence of a nickel-phosphine complex

Reaction of 1,1-dihalogeno-2-phenyl-1-alkenes (I) with phenylmagnesium bromide in the presence of NiCl2(dppp) in THF has been studied.Mono-cross-coupling accompanied by partial reduction gave (E)-1,2-diphenyl-1-alkenes (III) as the major products.Use of a large excess of Grignard reagent increased the yields of III and the (Z)-isomers (II), with a decrease in the yield of double cross-coupling products, 1,1,2-triphenyl-1-alkenes (IV).The highest ratio of the sum of the yields of the monophenylation products to the yield of the double cross-coupling product, (II+III)/IV=36.5, was found for the reaction of PhMgBr with 1,1-dibromo-2-phenylpropene (Ib) in a 12.0/1 molar ratio.A possible reaction mechanism is described.