202263-69-2

Upstream product

• 202263-73-8 2-cyclopentyl-4-(4-fluorophenyl)-7,7-dimethyl-3-(4-trifluoromethylbenzoyl)-4,6,7,8-tetrahydro-1H-quinolin-5-one 
• 4630-80-2 methyl cyclopentane carboxylate 
• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 202263-68-1 2-cyclopentyl-4-(4-fluorophenyl)-7,7-dimethyl-3-(4-trifluoromethylbenzoyl)-7,8-dihydro-6H-quinolin-5-one 

Downstream Products

• 202263-74-9 [5-(tert-butyl-dimethyl-silanyloxy)-2-cyclopentyl-4-(4-fluoro-phenyl)-7,7-dimethyl-5,6,7,8-tetrahydro-quinolin-3-yl]-(4-trifluoromethyl-phenyl)-methanone 
• 202263-76-1 (S)-5-(tert-Butyl-dimethyl-silanyloxy)-2-cyclopentyl-4-(4-fluoro-phenyl)-3-[(S)-fluoro-(4-trifluoromethyl-phenyl)-methyl]-7,7-dimethyl-5,6,7,8-tetrahydro-quinoline 

Relevant academic research and scientific papers

Fluorine-substitution in cholesteryl ester transfer protein inhibitors (CETP-inhibitors) - Biology, chemistry, SAR, and properties

The inhibition of the cholesteryl ester transfer protein (CETP) provides a method for the elevation of the high density lipoprotein cholesterol (HDL-C) level, i.e. the 'good' cholesterol. The expected anti-atherogenic effect of this approach is independen