202264-97-9

Upstream product

• 98-80-6 phenylboronic acid 
• 2213-63-0 2,3-dichloroquinoxaline 
• 1765-93-1 4-fluoroboronic acid 
• 7065-92-1 2-chloro-3-phenylquinoxaline 
• 536-74-3 phenylacetylene 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 405-29-8 (4-fluorophenyl)phenylacetylene 
• 95-54-5 1,2-diamino-benzene 
• 82677-84-7 1-(4-fluorophenyl)-3-phenylprop-2-yn-1-one 
• 3834-66-0 (4-fluorophenyl)phenylethanedione 

Downstream Products

• 1245801-43-7 9-phenyl-9'-[4-(3-phenylquinoxalin-2-yl)phenyl]-3,3'-bi(9H-carbazol) 

Relevant academic research and scientific papers

In water organic synthesis: Introducing itaconic acid as a recyclable acidic promoter for efficient and scalable synthesis of quinoxaline derivatives at room temperature

Substituted quinoxaline derivatives are traditionally synthesized by co-condensation of various starting materials. Herein, we describe a novel environmentally benign in water synthetic route for the synthesis of structurally and electronically diverse ninety quinoxalines with readily available substituted o-phenylenediamine and 1,2-diketones using cheap and biodegradable itaconic acid as a mild acid promotor in 1 hours. The reaction is performed at room temperature, which proceeds through cyclo-condensation reaction followed by obtaining the aforesaid nitrogen-containing heterocyclic adducts without performing the column chromatography up to 96% total yields. The simplicity, high efficiency, and reusable of the catalyst merits this reaction condition as “green synthesis” which enables it to be useful in synthetic transformations upto gram scale level.

NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME

The present invention relates to a novel compound, capable of improving efficiency, and low driving voltage and/or lifespan characteristics in an organic light emitting device, and to an organic light emitting device including the same. The novel compound

Gold-Catalyzed Oxidation of Internal Alkynes into Benzils and its Application for One-Pot Synthesis of Five-, Six-, and Seven-Membered Azaheterocycles

Internal alkynes have been shown to undergo oxidation to substituted benzils (1,2-diarylethane-1,2-diones) by α-picoline N-oxide in the presence of Ph3PAuNТf2 (5 mol-%). In addition to the unsubstituted benzil, the method allows preparing, under markedly mild conditions (50 °C in chlorobenzene), various non-symmetrical products, including heteroaromatic versions thereof which are much more difficult to obtain otherwise. This gold(I)-catalyzed transformation was integrated into one-pot reaction sequence delivering a range of 5- to 7-membered ring systems (imidazoles, quinoxalines, 1,2,4-triazines, pyrazines, and 1,4-diazepines), thus linking these important heterocyclic motifs to the internal alkyne reagent space.

Synthesis of quinoxalines through iodine-catalyzed one-pot annulation of alkynes with o-phenylenediamines

The synthesis of N-heterocycles of quinoxalines has been developed by an efficient protocol of one-pot annulation of alkynes with o-phenylenediamines. A variety of quinoxalines were prepared in good to high yields in the presence of catalytic amount of iodine as a catalyst.

Preparation method of polysubstitution quinoxalin derivatives

The invention discloses a preparation method of polysubstitution quinoxalin derivatives. The method has the reaction equation as follows (please see the equation in the description). By means of the method, quinoxalin derivatives which are not easy to obtain through other methods and have various substituent groups can be synthesized.

Ruthenium-catalyzed oxidation of alkynes to 1,2-diketones under room temperature and one-pot synthesis of quinoxalines

A ruthenium-catalyzed alkyne oxidation to 1,2-diketones using Oxone under room temperature is reported. Both substrate scope and mechanism were discussed. Notably, combination of the alkyne oxidation and condensation cyclization in one pot offers a very efficient and convenient entry into quinoxaline derivatives.