202275-04-5Relevant articles and documents
Convenient synthesis of enantiomerically enriched β-cyclopropylalaninol derivatives by kinetic resolution via (-)-sparteine-mediated deprotonation
Hense, Thomas,Hoppe, Dieter
, p. 1394 - 1398 (1997)
The racemic mixture of the protected β-cyclopropylalaninol derivative 11 was subjected to asymmetric deprotonation by means of sec-butyllithium/(-)-sparteine, resulting in a preferential abstraction of the α-pro-S-H in (R)-1; (S)-11 remains untouched.
