202330-74-3Relevant academic research and scientific papers
AZOLE-SUBSTITUTED PYRIDINE COMPOUND
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Paragraph 0671; 0672, (2019/01/08)
The present invention provides a compound represented by formula [I'| shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme, wherein the structure represented by formula [III] shown below represents any of the structures represented by formula group [IV] shown below, wherein R1 represents a hydrogen atom, a fluorine atom, methyl, etc.; R2, R3, and R4 each independently represent a hydrogen atom, a fluorine atom, or methyl; W represents a single bond, C1-3alkanediyl, or the formula -O-CH2CH2-; and ring A represents (a) substituted C4-6cycloalkyl, (b) substituted 4- to 6-membered saturated nitrogen-containing heterocyclyl, (c) substituted phenyl, (d) substituted pyridyl, (e) substituted 2,3-dihydrobenzofuran, (f) 4- to 6-membered saturated oxygen-containing heterocyclyl, etc.
AROMATIC RING COMPOUND
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Paragraph 0585; 0586, (2015/01/18)
Provided is an aromatic ring compound having a GPR40 agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity, and is useful as an agent for the prophylaxis or treatment of diabetes and the like.
Total synthesis of (±)-abieta-8, 11, 13-trien-7ss-ol
Zhang, Cheng-Lu,Bie, Ping-Yan,Peng, Xuan-Jia,Pan, Xin-Fu
, p. 429 - 432 (2007/10/03)
The first total synthesis of (±)-abieta-8,11,13-trien-7ss-ol (1) was accomplished, in which α-cyclocitral was used as the A ring synthon, and triphenylphosphonium chloride (9), which was obtained from mbromobenzyl alcohol (4) via five steps, as the C ring
Potassium Cryptate of a Macrobicyclic Ligand Featuring a Reducible Hexakis(phenylthio)benzene Electron-Acceptor Site
Mayor, Marcel,Lehn, Jean-Marie
, p. 2277 - 2285 (2007/10/03)
The synthesis and structural characterization of the macrobicyclic ligand 1 containing a reducible hexakis(phenylthio)benzene electron-acceptor site is described. It is based on the condensation of the tetraoxa-di-azamacrocycle 3 with a suitably functiona
