202345-17-3Relevant academic research and scientific papers
The asymmetric synthesis and in vitro characterization of succinyl mercaptoalcohol and mercaptoketone inhibitors of matrix metalloproteinases
Levin, Jeremy I.,DiJoseph, John F.,Killar, Loran M.,Sharr, Michele A.,Skotnicki, Jerauld S.,Patel, Dinesh V.,Xiao, Xiao-Yi,Shi, Lihong,Navre, Marc,Campbell, David A.
, p. 1163 - 1168 (2007/10/03)
A series of succinyl based mercaptoketones and diastereomeric mercaptoalcohols were prepared and evaluated in vitro as inhibitors of the matrix metalloproteinases collagenase-1 (MMP-1), stromelysin (MMP-3), and gelatinase-B (MMP-9).
