202406-65-3

Upstream product

• 994-30-9 triethylsilyl chloride 
• 75-24-1 trimethylaluminum 
• 1216963-74-4 lithium acetylide-ethylenediamine complex 
• 65291-30-7 (R)-(+)-trityl glycidyl ether 

Downstream Products

• 909016-48-4 (E)-(1S,2S,5R,11R,13R)-5-((1E,3E)-4-Bromo-buta-1,3-dienyl)-13-(tert-butyl-diphenyl-silanyloxy)-1-hydroxy-2,7,10,10-tetramethyl-4,15-dioxa-bicyclo[9.3.1]pentadec-7-ene-3,9-dione 
• 202406-76-6 (E)-(1S,2S,5R,11R,13R)-5-((1E,3Z)-4-Bromo-buta-1,3-dienyl)-13-(tert-butyl-diphenyl-silanyloxy)-1-hydroxy-2,7,10,10-tetramethyl-4,15-dioxa-bicyclo[9.3.1]pentadec-7-ene-3,9-dione 
• 202406-73-3 (E)-(1S,2S,5R,11R,13R)-13-(tert-Butyl-diphenyl-silanyloxy)-1-hydroxy-5-hydroxymethyl-2,7,10,10-tetramethyl-4,15-dioxa-bicyclo[9.3.1]pentadec-7-ene-3,9-dione 
• 202406-69-7 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((E)-(R)-2,6-dihydroxy-1,1,4-trimethyl-7-trityloxy-hept-3-enyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid 
• 202406-67-5 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((E)-(R)-2-hydroxy-1,1,4-trimethyl-6-triethylsilanyloxy-7-trityloxy-hept-3-enyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of the aglycon of aurisides A and B, cytotoxic macrolide glycosides of marine origin

The synthesis of the aglycon of aurisides A and B was achieved from (R)-pantolactone in 29 steps using the Nozaki reaction and the Yamaguchi macrolactonization as key steps.