202407-26-9 Usage
Uses
Used in Biochemical Research:
L-4-HYDROXYPHENYLALANINE-13C9,15N is used as a labeled analogue in biochemical research for studying the metabolism and biosynthesis of L-Tyrosine and its derivatives. The incorporation of 13C and 15N isotopes enables researchers to track the compound's metabolic pathways and interactions with enzymes and other biomolecules.
Used in Neurochemistry:
In neurochemistry, L-4-HYDROXYPHENYLALANINE-13C9,15N is used as a labeled precursor for the synthesis of neurotransmitters such as dopamine, norepinephrine, and epinephrine. The stable isotopes allow for the investigation of neurotransmitter dynamics, release, and uptake in the brain, providing insights into neurological disorders and the development of therapeutic interventions.
Used in Mass Spectrometry:
L-4-HYDROXYPHENYLALANINE-13C9,15N is utilized in mass spectrometry as an internal standard for the quantification and identification of L-Tyrosine and its metabolites. The presence of 13C and 15N isotopes provides a distinct mass signature, facilitating accurate measurement and analysis in complex biological samples.
Used in Pharmaceutical Development:
In the pharmaceutical industry, L-4-HYDROXYPHENYLALANINE-13C9,15N is used as a labeled compound for the development and optimization of drugs targeting L-Tyrosine metabolism or related pathways. The stable isotopes can aid in the assessment of drug efficacy, pharmacokinetics, and pharmacodynamics, as well as in the identification of potential drug-drug interactions.
Used in Nutritional Studies:
L-4-HYDROXYPHENYLALANINE-13C9,15N is employed in nutritional studies to investigate the role of L-Tyrosine in various physiological processes, such as protein synthesis, energy metabolism, and the synthesis of neurotransmitters. The stable isotopes allow for the tracking of L-Tyrosine intake, absorption, and utilization in the body, contributing to a better understanding of its nutritional importance and requirements.
Check Digit Verification of cas no
The CAS Registry Mumber 202407-26-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,2,4,0 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 202407-26:
(8*2)+(7*0)+(6*2)+(5*4)+(4*0)+(3*7)+(2*2)+(1*6)=79
79 % 10 = 9
So 202407-26-9 is a valid CAS Registry Number.
202407-26-9Relevant academic research and scientific papers
STABLE ISOTOPE-LABELED AMINO ACID, METHOD OF INTEGRATING THE SAME INTO TARGET PROTEIN, METHOD OF NMR STRUCTURAL ANALYSIS OF PROTEIN AND PROCESS FOR PRODUCING SITE-SELECTIVE STABLE ISOTOPE-LABELED FUMARIC ACID AND TARTARIC ACID
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Page 22, (2010/02/08)
The present invention provides a stable isotope-labeled amino acid which is at least one of amino acids constituting a protein and which has at least one of the following labeling patterns:(a) hydrogen atoms except at least one hydrogen atom in one or more methylene groups are deuterated,(b) hydrogen atoms in one of prochiral gem-methyl groups are completely deuterated,(c) hydrogen atoms in prochiral methyl groups are partially deuterated, and(d) all hydrogen atoms except one of them in methyl group are deuterated and hydrogen atoms in the aromatic ring are partially deuterated. With the stable isotope-labeled amino acid, the deuteration of protein can be attained without damaging the NMR sensitivity of remaining hydrogen nucleus and, in addition, the rapid, accurate analysis of NMR spectrum of a high-molecular protein which is beyond the limitation in the prior art and the determination of the stereo-structure can be performed at the same time.
