20241-68-3

Basic information

• Product Name: 4-Amino-N-(3-(2-hydroxyethyl)sulfonylphenyl)benzamide
• Synonyms: 4-amino-n-(3-(2-hydroxyethyl)sulfonylphenyl)benzamide;4-Amino-N-[3-(2-hydroxyethylsulfonyl)phenyl]benzamide;4-amino-N-[3-[(2-hydroxyethyl)sulphonyl]phenyl]benzamide;N-P-AMINOBENZOYL-M-(BETA-HYDROXYETHYL SULFONE)ANILINE;3-(4-AMINOBENZOYL)AMINOPHENYL-BETA-HYDROXYETHYL SULFONE;N-P-AMINOBENZOYL-M-(SS-HYDROXYETHYL SULFONE)ANILINE;3-(4-Aminobenzoylamino)phenyl β-hydroxyethyl sulfone;3-(4'-Aminobenzoylamino)phenyl-β-hydroxyethyl sulfone
• CAS NO: 20241-68-3
• Molecular Formula: C₁₅H₁₆N₂O₄S
• Molecular Weight: 320.36
• EINECS: 243-629-8
• Mol File: 20241-68-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 150-152 °C
• Boiling Point: 538.6°Cat760mmHg
• Flash Point: 279.5°C
• Appearance: /
• Density: 1.415g/cm³
• Vapor Pressure: 1.98E-12mmHg at 25°C
• Refractive Index: 1.655
• PKA: 13.56±0.10(Predicted)
• CAS DataBase Reference: 4-Amino-N-(3-(2-hydroxyethyl)sulfonylphenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-N-(3-(2-hydroxyethyl)sulfonylphenyl)benzamide(20241-68-3)
• EPA Substance Registry System: 4-Amino-N-(3-(2-hydroxyethyl)sulfonylphenyl)benzamide(20241-68-3)

Safety Data

• Hazardous Substances Data: 20241-68-3(Hazardous Substances Data)

Usage

General Description

4-Amino-N-(3-(2-hydroxyethyl)sulfonylphenyl)benzamide is a chemical compound that falls under the category of sulfonamide derivatives. It is an organic compound with a molecular formula of C15H16N2O4S and a molecular weight of 320.36 g/mol. It is a potential drug candidate and has been studied for its potential pharmacological properties. 4-Amino-N-(3-(2-hydroxyethyl)sulfonylphenyl)benzamide contains an amino group, a benzamide group, and a sulfonylphenyl group, making it useful in medicinal chemistry and pharmaceutical applications. The presence of the hydroxyethyl group makes it a potential candidate for various biological activities, and its structure offers potential for further modification and drug development.

InChI:InChI=1/C15H16N2O4S/c16-12-6-4-11(5-7-12)15(19)17-13-2-1-3-14(10-13)22(20,21)9-8-18/h1-7,10,18H,8-9,16H2,(H,17,19)

Relevant articles and documents

Process for the preparation of sulfuric acid semiester ethylsulfonyl compounds of aminophenols, aminobenzanilides or phenylpyrazolones by esterification with sulfuric acid and/or sulfur trioxide in a kneader

An improved and novel process had been found for the esterification of aminophenol, amino-benzanilide and pyrazolone compounds containing a β-hydroxyethylsulfonyl group, by means of sulfuric acid or sulfur trioxide which improvement is characterized by that the esterification is performed in a machine which is operating with a kneading action and effect, using per mol β-hydroxyethylsulfonyl compound 1 to 2.5 times the equivalent molar amount of concentrated sulfuric acid, oleum or sulfur trioxide. This novel process has the great advantage that great amounts of sulfuric acid are saved which could charge the waste water, also in form of sodium sulfate formed after the required neutralization. Furthermore, the β-sulfatoethylsulfonyl compounds formed as end-products in the esterification process are prepared by this novel process in higher yields, in a higher degree of esterification rate and in a higher purity. They are obtained in form of a powder or plastic mass from the kneading machine, which is well transportable and storable, and can advantageously used in the form of this consistency, without intermediate isolation of the pure β-sulfato compound itself, directly for the preparation of azo dyestuffs which are poor of inert salts, possess a high tinctorial strength and purity.