202476-26-4

Usage

Derivative

pyrazole

Functional group

carbonyl chloride

Use

reagent for introducing carbonyl chloride group into other molecules

Potential application

pharmaceutical research and development

Safety

handle and use according to proper safety protocols and regulations.

Upstream product

• 191614-02-5 5-fluoro-1,3-dimethyl-1H-pyrazole-4-carbonyl fluoride 
• 116046-53-8 2-trifluoromethyl-3-oxobutanoic acid ethyl ester 
• 1027991-91-8 5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxylic acid 
• 1365265-23-1 ethyl 5-fluoro-1,3-dimethylpyrazole-4-carboxylate 

Downstream Products

• 1207172-45-9 N-[(3-chlorobiphenyl-4-yl)methyl]-N-cyclopropyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide 
• 1207183-07-0 N-[2-(biphenyl-4-yloxy)ethyl]-N-cyclopropyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide 
• 1350893-71-8 N-cyclopropyl-N-{[dimethyl(phenyl)silyl]methyl}-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide 
• 494793-45-2 5-fluoro-1,3-dimethyl-N-[2-(1,3,3-trimethylbutyl)phenyl]-1H-pyrazole-4-carboxamide 
• 393877-05-9 5-fluoro-1,3-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-pyrazole-4-carboxamide 
• 202475-97-6 N-(2-isopropyl)-cyclohexyl-5-fluoro-1,3-dimethyl-pyrazole-4-carboxamide 
• 851758-04-8 5-fluoro-1,3-dimethyl-1H-pyrazol-4-carboxylic acid [2-(3-methyl-butyryl)-phenyl]-amide 

Relevant academic research and scientific papers

Syntheses of 2-(trifluoromethyl)-1,3-dicarbonyl compounds through direct trifluoromethylation with CF3I and their application to fluorinated pyrazoles syntheses

Direct trifluoromethylation of 1,3-dicarbonyl compounds with CF 3I in the presence of a Fenton reagent in dimethylsulfoxide was investigated. 1,3-Diketones, 3-oxocarboxylates and 3-oxocarboxamides were readily trifluoromethylated at the methyle

Method for Producing 5-Fluoro-1,3-Dialkyl-1H-Pyrazol-4-Carboxylic Acid Chlorides

The present invention relates to a novel process for preparing known 5-fluoro-1,3-dialkyl-1H-pyrazole-4-carbonyl chlorides which can be used as starting materials for active fungicidal ingredients.