202646-05-7Relevant academic research and scientific papers
A novel photoaffinity label for the dopamine transporter based on N-substituted 3α-[bis(4'-fluorophenyl)methoxy]tropane
Agoston, Gregory E.,Vaughan, Roxanne,Lever, John R.,Izenwasser, Sari,Terry, Phyllis D.,Newman, Amy Hauck
, p. 3027 - 3032 (2007/10/03)
A novel photoaffinity label for the dopamine transporter (DAT) based on N-substituted 3α-[bis(4'-fluorophenyl)methoxy] tropane has been synthesized in five steps and has been characterized. Preliminary binding studies indicated this ligand bound irreversi
Novel N-substituted 3α-[bis(4'-fluorophenyl)methoxy]tropane analogues: Selective ligands for the dopamine transporter
Agoston, Gregory E.,Wu, Jae H.,Izenwasser, Sari,George, Clifford,Katz, Jonathan,Kline, Richard H.,Newman, Amy Hauck
, p. 4329 - 4339 (2007/10/03)
A series of N-substituted 3α-[bis(4'-fluorophenyl)methoxy]tropane analogues has been prepared that function as dopamine uptake inhibitors. The N-methylated analogue of this series had a significantly higher affinity for the dopamine transporter than the p
