20265-96-7Relevant articles and documents
Deoxygenation of Nitrous Oxide and Nitro Compounds Using Bis(N-Heterocyclic Silylene)Amido Iron Complexes as Catalysts
Chen, Xi,Driess, Matthias,Du, Shaozhi,Mo, Zhenbo,Wang, Hao
supporting information, (2021/12/03)
Herein, we report the efficient degradation of N2O with a well-defined bis(silylene)amido iron complex as catalyst. The deoxygenation of N2O using the iron silanone complex 4 as a catalyst and pinacolborane (HBpin) as a sacrificial reagent proceeds smoothly at 50 °C to form N2, H2, and (pinB)2O. Mechanistic studies suggest that the iron–silicon cooperativity is the key to this catalytic transformation, which involves N2O activation, H atom transfer, H2 release and oxygenation of the boron sites. This approach has been further developed to enable catalytic reductions of nitro compounds, producing amino-boranes with good functional-group tolerance and excellent chemoselectivity.
Synthesis method of 4-chlorobenzene cyanoguanidine
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Paragraph 0011-0017, (2021/02/10)
The invention provides a synthetic method of 4-chlorobenzene cyanoguanidine. According to the method, diazonium p-chlorobenzene chloride and dicyandiamide are taken as main raw materials, and a targetcompound is synthesized by two steps. The preparation method comprises the following steps: carrying out coupling reaction on the diazonium p-chlorobenzene chloride and the dicyandiamide in the presence of sodium carbonate to obtain an intermediate 4-chlorphenyl azo cyanoguanidine; then putting the intermediate into diluted hydrochloric acid, performing heating and discharging nitrogen to obtaina crude product; and dissolving the crude product in a dilute sodium hydroxide solution, removing color by activated carbon, performing neutralizing by adding acid, carrying out suction filtration andwashing, and performing drying to obtain a final product 4-chlorobenzene cyanoguanidine. Chlorinated diazonium p-chlorobenzene needs to be prepared for immediate use and is prepared by reacting 4-chloroaniline with sodium nitrite under an acidic condition. The preparation method is simple, mild in reaction condition, free of organic solvent, simple and convenient in subsequent treatment, safe andenvironmentally friendly; and meanwhile, the obtained product is relatively good in purity and relatively high in yield, and the method is a relatively good and safe method for synthesizing the aromatic guanidino compound, namely, the 4-chlorobenzene cyanoguanidine.
Sustainable and Scalable Fe/ppm Pd Nanoparticle Nitro Group Reductions in Water at Room Temperature
Gabriel, Christopher M.,Parmentier, Michael,Riegert, Christian,Lanz, Marian,Handa, Sachin,Lipshutz, Bruce H.,Gallou, Fabrice
, p. 247 - 252 (2017/02/26)
An operationally simple and general process for the safe and selective reduction of nitro groups utilizing ppm Pd supported on Fe nanomaterials in aqueous solution of designer surfactant TPGS-750-M has been developed and successfully carried out at a 100 mmol scale. Preferred use of KBH4 as the hydride source, at ambient temperature and pressure, lends this process suitable for a standard reaction vessel alleviating the need for specialized hydrogenation equipment. Calorimetry data parallel those expected for a classical nitro group reduction when measuring the heat of reaction (-896 to -850 kJ/mol).
