20272-25-7Relevant academic research and scientific papers
Calcium(II)- And Triflimide-Catalyzed Intramolecular Hydroacyloxylation of Unactivated Alkenes in Hexafluoroisopropanol
Qi, Chenxiao,Yang, Shengwen,Gandon, Vincent,Leb?uf, David
supporting information, p. 7405 - 7409 (2019/10/02)
We report an efficient intramolecular hydroacyloxylation of unactivated alkenes, offering a streamlined access to relevant γ-lactones, which features the utilization of either a calcium(II) salt or triflimide as a catalyst in hexafluoroisopropanol. This method could be applied to the synthesis of natural products and the late-stage functionalization of natural and bioactive molecules. Additionally, DFT computations were used to elucidate the twist of reactivity observed between the hydroamidation and hydroacyloxylation of unactivated alkenes regarding the formation of 5- and 6-membered rings.
(HMe 2 SiCH 2) 2: A Useful Reagent for B(C 6 F 5) 3 -Catalyzed Reduction-Lactonization of Keto Acids: Concise Syntheses of (-)- cis -Whisky and (-)- cis -Cognac Lactones
Xie, Hengmu,Lu, Ji,Gui, Yingying,Gao, Lu,Song, Zhenlei
supporting information, p. 2453 - 2459 (2017/10/06)
(HMe 2 SiCH 2) 2 has been utilized as a useful reagent for B(C 6 F 5) 3 -catalyzed reduction-lactonization of keto acids to synthesize γ- and δ-lactones. The process led concisely to (-)- cis -whisky and (-)- cis -cognac lactones in respective overall yields of 32% and 36%.
Small changes result in large differences: Discovery of (-)-incrustoporin derivatives as novel antiviral and antifungal agents
Lu, Aidang,Wang, Jinjin,Liu, Tengjiao,Han, Jian,Li, Yinhui,Su, Min,Chen, Jianxin,Zhang, Hui,Wang, Lizhong,Wang, Qingmin
, p. 8799 - 8807 (2014/11/08)
On the basis of the structure of natural product (-)-incrustoporin (1), a series of lactone compounds 4a-i and 5a-i were designed and synthesized from nitroolefin. The antiviral and antifungal activities of these compounds were evaluated in vitro and in v
Phase-Transfer-Catalyzed Conversion of Alkynes to Lactones Induced by Manganase Carbonyl Complexes
Wang, Jin-Xian,Alper, Howard
, p. 273 - 275 (2007/10/02)
Alkynes react with methyl iodide, bromopentacarbonylmanganese (or dimanganese decacarbonyl), and carbon monoxide, under phase-transfer catalysis conditions, to give γ-butyrolactones; the reaction conditions are mild , and the process is a regiospecific one
