20278-51-7

Basic information

• Product Name: DIMETHYLMETHYLPHOSPHONITE
• Synonyms: DIMETHYLMETHYLPHOSPHONITE
• CAS NO: 20278-51-7
• Molecular Formula: C₃H₉O₂P
• Molecular Weight: 108.08
• Product Categories: Phosphorus compounds
• Mol File: 20278-51-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 69.3 °C at 760 mmHg
• Appearance: /
• Vapor Pressure: 147mmHg at 25°C
• CAS DataBase Reference: DIMETHYLMETHYLPHOSPHONITE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYLMETHYLPHOSPHONITE(20278-51-7)
• EPA Substance Registry System: DIMETHYLMETHYLPHOSPHONITE(20278-51-7)

Safety Data

• Hazardous Substances Data: 20278-51-7(Hazardous Substances Data)

Usage

General Description

DIMETHYLMETHYLPHOSPHONITE is a chemical compound with the formula (CH3)2P(O)CH3. It is a colorless, flammable liquid with a faint odor, and is primarily used as a chemical intermediate in the synthesis of organophosphorus compounds and pesticides. DIMETHYLMETHYLPHOSPHONITE is highly toxic, and exposure to it can cause irritation to the skin, eyes, and respiratory system. In addition, it is classified as a hazardous material and requires careful handling and storage to prevent accidental release and potential harm to human health and the environment.

InChI:InChI=1/C3H9O2P/c1-4-6(3)5-2/h1-3H3

Upstream product

• 74-87-3 methylene chloride 
• 3743-07-5 dimethyl chlorophosphite 
• 756-79-6 dimethyl methane phosphonate 
• 67-56-1 methanol 
• 676-83-5 methyldichlorophosphane 
• 71196-16-2 2-methyl-2,3-dihydro-benzo[1,3,2]oxazaphosphole 
• 14937-39-4 methyl-bis(dimethylamino)phosphine 
• 431-47-0 trifluoroacetic acid-methyl ester 

Downstream Products

• 18755-36-7 O-ethyl O-methyl methylphosphonate 
• 756-79-6 dimethyl methane phosphonate 
• 18733-15-8 methyl 3-(dimethoxyphosphinyl)propionate 
• 38316-42-6 methylphosphonous acid diphenyl ester 
• 60170-77-6 C₁₀H₁₇AsO₄P₂ 
• 31641-49-3 C₁₀H₁₇NO₄P₂ 

Relevant articles and documents

Preparation method of monoalkyl phosphinic acid dialkyl ester, dialkyl phosphonate and metal salt thereof

The invention relates to the technical field of phosphonate synthesis, and discloses a preparation method of monoalkyl phosphinic acid dialkyl ester, which comprises the following steps: reacting monoalkyl phosphonic acid dialkyl ester under the action of a silicon-hydrogen-containing reducing agent to obtain a monoalkyl phosphinic acid dialkyl ester, wherein the reaction formula is shown in the specification, each R1 is independently an alkyl group with 1-10 carbon atoms, and the silicon-hydrogen-containing reducing agent is chlorine-containing and/or hydrogen-containing silane. The inventionalso discloses a method for preparing dialkyl phosphonate by isomerizing the monoalkyl phosphinic acid dialkyl ester, and further discloses a preparation method of dialkyl phosphinic acid and metal salt thereof. The method is mild in process condition and easy to implement in industrialization, aftertreatment is simple and feasible, the product purity reaches up to 98-99%, dialkyl phosphinic acidobtained through hydrolysis of dialkyl phosphonic acid alkyl ester can also be applied to extraction of metal ions or rare earth, and extra purification is not needed.

Method using one-pot method to prepare 4-(methyl hydroxyl phosphoryl)-2-carbonyl butyric acid

The invention discloses a method using a one-pot method to prepare 4-(methyl hydroxyl phosphoryl)-2-carbonyl butyric acid. The method is characterized in that methyl phosphorus dichloride is allowed to react with methanol to prepare methyl dimethoxy phosphorus as shown in formula (I), the methyl dimethoxy phosphorus is allowed to directly react with methyl acrylate to prepare a compound as shown in formula (II) without separation and purification, the compound as shown in formula (II) is allowed to have condensation reaction with diethyl oxalate to prepare a compound as shown in formula (III), and the compound as shown in formula (III) is allowed to react with hydrochloric acid to prepare the 4-(methyl hydroxyl phosphoryl)-2-carbonyl butyric acid. The method using the one-pot method to prepare the 4-(methyl hydroxyl phosphoryl)-2-carbonyl butyric acid has the advantages that the steps of the method are orderly connected, the method is short in synthesizing route, high in reaction yield, simple to operate and especially suitable for industrial production, and enterprise market competitiveness is enhanced.

Preparation method of dialkyl methylphosphonite

The invention relates to a preparation method of dialkyl methylphosphonite. tertiary amine with pKa greater than 10 is adopted as the acid binding agent, methyl phosphonic dichloride and alcohol react in a solvent, and the mole ratio of the methyl phosphonic dichloride, alcohol and tertiary amine is 1:2.0-2.4:2.0-2.4, the produced tertiary amine hydrochloride is neutralized with a caustic soda aqueous solution, and the solvent and tertiary amine obtained by evaporation is recycled and reused. The alkyl of the dialkyl methylphosphonite is straight chain and side chain alkane or alkene of aliphatic C1-C4, the alcohol refers to methanol, ethanol, propanol, isopropanol, allyl alcohol, n-butanol, isobutanol and the like, the tertiary amine refers to tertiary fatty amine, and also refers to fatty group and aromatic mixed tertiary amine, at the same time, the pKa of the tertiary amine is required to be greater than 10, and the tertiary amine can include triethylamine, tripropylamine and tributylamine.