202808-48-8

Upstream product

• 493-72-1 5-phenyl-cyclohexane-1,3-dione 
• 100-46-9 benzylamine 

Downstream Products

• 1158819-91-0 C₂₈H₂₃NO₄ 
• 1255534-38-3 1-benzyl-3-(4-fluorophenyl)-6-phenyl-6,7-dihydro-1H-indol-4(5H)-one 
• 1255534-37-2 1-benzyl-3,6-diphenyl-6,7-dihydro-1H-indol-4(5H)-one 
• 1158820-10-0 5-benzyl-7-phenyl-7,8-dihydroindeno[1,2-b]indole-9,10(5H,6H)-dione 
• 1350229-16-1 5-benzyl-9-hydroxy-7-phenylindeno[1,2-b]indole-10(5H)-one 
• 1562377-17-6 C₃₃H₃₉NO₃Si 
• 1562377-11-0 C₂₇H₂₅NO₃ 
• 36646-70-5 3-amino-5-phenylcyclohex-2-en-1-one 
• 1402907-00-9 1-benzyl-2,6,7,8-tetrahydro-2,2-dimethyl-7-phenylquinolin-5(1H)-one 

Relevant academic research and scientific papers

Cu catalyzed cross-dehydrogenative coupling reaction for the synthesis of 3-hydroxy-2-pyrrolidinones

A new convenient strategy for the synthesis of 3-hydroxy-2-pyrrolidinone derivatives featuring regioselective C–C coupling has been developed. This is a Cu (II) catalyzed cross dehydrogenative coupling (CDC) involving enamino-ketones of benzyl amines and di-alkyl acetylenedicarboxylate, followed by cyclization by primary amines. TBHP (tert-butyl hydroperoxide) has been used as the oxidant to promote the coupling protocol. This synthetic route principally demonstrates the scope of CDC reaction and also applicable to gram-scale synthesis.

Diels-Alder construction of regiodifferentiated meta-amino phenols and derivatives

Synthetic access to regiodifferentiated meta-amino phenols is described. The strategy relies upon distinct deprotonation conditions to afford regioisomeric thermodynamic and kinetic dienes that undergo a tandem Diels-Alder and retro-Diels-Alder sequence with assorted acetylenic dienophiles to afford a range of aromatic products.

Efficient synthesis of tetrahydroquinolinones by acetic acid-mediated formal [3+3] cycloaddition

A simple and efficient method to synthesize a variety of tetrahydroquinolinones was successfully achieved by reacting various β-enaminones with several α,β-unsaturated aldehydes. This strategy can be viewed as a Bronsted acid-mediated formal [3+3] cycloaddition. Springer-Verlag 2012.

Partially saturated indeno[1,2-b]indole derivatives via deoxygenation of heterocyclic α-hydroxy-N,O-hemiaminals

A series of 3-aminocyclohex-2-enones were reacted with indane-1,2,3-trione monohydrate (ninhydrin) yielding 4b,9b-dihydroxyindeno[ 1,2-b]indoles that were deoxygenated to indeno[1,2-b]indoles. Georg Thieme Verlag Stuttgart.