2028281-87-8

Basic information

• Product Name: Azido-PEG4-(CH2)3OH
• Synonyms: Azido-PEG4-(CH2)3OH;N3-PEG4-CH2CH2CH2OH
• CAS NO: 2028281-87-8
• Molecular Formula: C11H23N3O5
• Molecular Weight: 277.31742
• Mol File: 2028281-87-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Azido-PEG4-(CH2)3OH(CAS DataBase Reference)
• NIST Chemistry Reference: Azido-PEG4-(CH2)3OH(2028281-87-8)
• EPA Substance Registry System: Azido-PEG4-(CH2)3OH(2028281-87-8)

Safety Data

• Hazardous Substances Data: 2028281-87-8(Hazardous Substances Data)

Usage

Description

Azido-PEG4-(CH2)3OH is a PEG compound that features a three-carbon chain connecting the PEG fragment to the hydroxyl (OH) group, and it contains four PEG units. The azide group present in the compound can readily react with alkyne, BCN, and DBCO through Click Chemistry, a versatile and efficient method for creating covalent bonds.

Uses

Used in Bioconjugation Applications:
Azido-PEG4-(CH2)3OH is used as a bioconjugation agent for attaching various biomolecules, such as proteins, peptides, and nucleic acids, to other molecules or surfaces. The presence of the azide group allows for efficient and selective coupling through Click Chemistry, facilitating the formation of stable and well-defined bioconjugates.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Azido-PEG4-(CH2)3OH is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of therapeutic agents. The PEGylation provided by this compound can also reduce the immunogenicity and non-specific interactions of drug molecules, enhancing their overall therapeutic efficacy.
Used in Materials Science:
Azido-PEG4-(CH2)3OH is utilized as a building block in the development of functional materials, such as hydrogels, micelles, and nanoparticles. The PEG-based structure endows these materials with favorable properties, such as biocompatibility, stealth characteristics, and tunable physical properties. The azide group further enables their post-modification and functionalization through Click Chemistry for specific applications.
Used in Chemical Synthesis:
In organic synthesis, Azido-PEG4-(CH2)3OH serves as an intermediate or a reactant for the preparation of various PEGylated compounds. The azide group can be used to introduce a wide range of functional groups via Click Chemistry, allowing for the synthesis of diverse PEG-based molecules with tailored properties and applications.