2028281-89-0 Usage
Uses
Used in Pharmaceutical Industry:
m-PEG4-(CH2)8-phosphonic acid ethyl ester is used as a pharmaceutical agent for improving the solubility and bioavailability of hydrophobic drugs. The PEG linker aids in reducing the immunogenicity and increasing the stability of drug molecules, leading to enhanced therapeutic effects.
Used in Bioconjugation:
In the field of bioconjugation, m-PEG4-(CH2)8-phosphonic acid ethyl ester serves as a versatile linker for attaching biologically active molecules, such as peptides, proteins, or nucleic acids, to various surfaces or nanoparticles. The phosphonate group provides a stable and reactive handle for covalent attachment, while the PEG linker offers increased solubility and reduced non-specific interactions.
Used in Material Science:
m-PEG4-(CH2)8-phosphonic acid ethyl ester is utilized in material science for the development of functional coatings and surfaces. The phosphonate group can form strong bonds with metal oxide surfaces, while the PEG linker imparts antifouling properties, making it ideal for applications such as corrosion resistance, self-healing materials, or biosensors.
Used in Nanotechnology:
In nanotechnology, m-PEG4-(CH2)8-phosphonic acid ethyl ester is employed as a stabilizing agent for the synthesis of nanoparticles. The PEG linker enhances the dispersion and stability of nanoparticles in aqueous media, while the phosphonate group can be used for further functionalization or targeting purposes.
Overall, m-PEG4-(CH2)8-phosphonic acid ethyl ester is a versatile molecule with applications spanning across various industries, thanks to its unique combination of a hydrophilic PEG linker and a reactive phosphonate group.
Check Digit Verification of cas no
The CAS Registry Mumber 2028281-89-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,2,8,2,8 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2028281-89:
(9*2)+(8*0)+(7*2)+(6*8)+(5*2)+(4*8)+(3*1)+(2*8)+(1*9)=150
150 % 10 = 0
So 2028281-89-0 is a valid CAS Registry Number.
2028281-89-0Relevant academic research and scientific papers
Okada, Yohei,Ishikawa, Kodai,Maeta, Naoya,Kamiya, Hidehiro
, p. 1853 - 1858 (2018)
For effective application of nanoparticles, their amenability to in-solution processing must be addressed, and stable, homogeneous solvent conditions are required. Although organic ligands have been used as surface-modifying reagents for nanoparticles to increase their colloidal stability and homogeneity in solution, the structure–function relationships of nanoparticle–ligand complexes remain elusive and controversial. Herein, a series of novel amphiphilic small-molecule ligands were designed, synthesized, and applied as surface-modifying reagents for aqueous, transparent TiO2 and ZrO2 nanoparticles. The colloidal stability of the resulting nanoparticle–ligand complexes was found to depend not only on the chain length, but also on the relative balance between hydrophobicity and hydrophilicity. The structure of the ligands can be fine-tuned to achieve “flexible colloidal stability”, thus significantly increasing complex stability in a variety of organic solvents.
