20288-72-6

Upstream product

• 2301-80-6 N-methyl-4-methylpyridinium iodide 
• 123-08-0 4-hydroxy-benzaldehyde 
• 108-89-4 picoline 
• 31067-32-0 1-(4-pyridyl)-2-(4-hydroxyphenyl)ethene 

Downstream Products

• 23302-83-2 4-[(1-methyl-4(1H)-pyridinylidene)-ethylidene]-2,5-cyclohexadiene-1-one 

Relevant academic research and scientific papers

A turn-on fluorescence probe for hydrogen sulfide in absolute aqueous solution

A turn-on hydrogen sulfide (H2S) fluorescence probe, 4-{2-[4-(2,4-dinitrophenoxy)-phenyl]-vinyl}-1-methyl-pyridinium iodide (DPPVP), based on the thiolysis reaction of dinitrophenyl ethers (DNP) has been proposed. Pyridinium structure enhanced the water solubility of DPPVP, which could quickly respond to H2S in absolute PBS solution and the fluorescence spectra of DPPVP at 520 nm were turned on by H2S. The spectra results exhibited that DPPVP could sensitively detect H2S with satisfied linear range (0–40 μM) and detection limit (13.4 nM). The high selectivity for H2S against biothiols was attributed to the significant difference in the pKa and the molecular size. Moreover, DPPVP has been successfully used for detecting H2S in vegetable.

Ultrasonic assisted synthesis of styrylpyridinium dyes: Optical properties and DFT calculations

The ultrasonic technique has received considerable attention in several fields; in particular, it gained rapid momentum in organic synthesis due to the larger reaction rates, milder reaction conditions, and better yields. We report herein a facile synthes

Hemicyanine-based copper ion ratiometric fluorescent probe and preparation and application thereof

The invention relates to a hemicyanine-based copper ion ratiometric fluorescent probe and preparation and application thereof. The molecular formula of the fluorescent probe is C20H17IN2O2; the preparation of the fluorescent probe comprises the steps that 1, 4-picoline and iodomethane react to obtain 1,4-lutidine iodate which is a compound 1; 2, the compound 1 and 4-hydroxybenzaldehyde react to obtain 4-(4-hydroxyl-styryl)-1-picoline iodate which is a compound 2; 3, the compound 2 and 2-picolinic acid react to obtain a copper ion ratiometric fluorescent probe 4-(4-picolinate-styryl)-1-picoline iodate which is a compound 3. According to the application of the fluorescent probe, the fluorescent probe and copper ions react in a pure water solution, and changes of the ratio (F503 nm/F448 nm) of fluorescence intensities at two different emission wavelengths are used for detecting whether copper ions exist or not. The probe is simple in preparation and treatment process, molecules of the fluorescent probe are in a copper ion and other positive ion coexistence system, and the high selectivity and sensitivity are shown.

Ratiometric fluorescent probes for hydrogen peroxide from a focused library

Light shifting: Ratiometric fluorescent probes for hydrogen peroxide (H2O2) were developed through a focused library strategy. One of the probes in the library, showed a redshift of over 100nm and an increase of over 30-fold in the emission intensity ratio (see scheme). This probe was utilized to detect H2O2 generated during glucose oxidation. Copyright

Fluorescent neuroactive probes based on stilbazolium dyes

A set of spectrally diverse stilbazolium dyes was identified in an uptake assay using cultured brainstem and cerebellum cells isolated from e19 chicks. Pretreatment of cells with indatraline, a monoamine reuptake inhibitor, allowed identification of dyes

Local viscosity analysis of triblock copolymer micelle with cyanine dyes as a fluorescent probe

The local viscosity of Pluronic F127 triblock copolymer micelles in water was determined with cyanine dyes as fluorescent probes. These dyes show very weak fluorescence at a low temperature, but show enhanced fluorescence at a temperature higher than the

The aggregation of the merocyanine dyes, depending of the type of the counterions

Counterions affect on the substructures formation in the case of the merocyanine dye, 1-methyl-4-[2-(4-hydroxyphenyl)ethenyl)]piridinium] hydrogensquarate both in gas and condense phase. Spectroscopically and structural elucidation of these aggregates have been performed, using solid-state conventional and linear-polarized IR-spectroscopy of oriented colloids as a nematic liquid crystal suspension, UV-vis spectroscopy, HPLC tandem ESI mass spectrometry, 1H and 13C NMR, TGV and DSC. Quantum chemical DFT calculations have been carried out as well. Experimental and theoretical data are compared with analogous ones of corresponding iodide salt of dye studied.

Combinatorial approach to organelle-targeted fluorescent library based on the styryl scaffold

The first fluorescent styryl dye library with a broad color range was synthesized by combinatorial condensation of various aldehydes and methyl pyridinium compounds, and their applications as organelle specific staining probes were demonstrated. Copyright