202991-96-6

Usage

Type of compound

Heterocyclic amine

Structural components

Morpholine and piperazine rings

Industrial application

Building block for the synthesis of various drugs

Medicinal uses

Antipsychotic and antidepressant medications

Research potential

Treating neurological and psychiatric disorders

Chemical reactivity

Utilized in the synthesis of other heterocyclic compounds

Safety precautions

Proper handling and safety measures required

Upstream product

• 874841-73-3 tert-butyl 4-(morpholin-2-ylmethyl)piperazine-1-carboxylate 

Relevant academic research and scientific papers

BICYCLIC PYRIMIDINE DERIVATIVES

[wherein m and n may be the same or different and each represents an integer of 1 to 3 wherein m + n is 4 or less; R1 represents NR4R5 (wherein R4 and R5 may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl or the like); R2 represents the above Formula (II), Formula (IV) or the like; A represents a single bond, -C(=O)-, -SO2-, -OC(=O)- or the like; and R3 represents substituted or unsubstituted lower alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aralkyl or the like]ψBicyclic pyrimidine derivatives represented by the above Formula (I), or quaternary ammonium salts thereof, or pharmaceutically acceptable salts thereof, or the like, are provided. These have anti-inflammatory activities or modulation activities on the functions of TARC and/or MDC and are useful for treating and/or preventing a disease which is related to T cells, such as an allergic disease, an autoimmune disease or transplant rejection.