203056-35-3

Upstream product

• 1350716-23-2 (R)-N-[(S)-1-phenylethyl]-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-buten-1-amine 
• 1350716-16-3 (R)-N-allyl-N-[(S)-1-phenylethyl]-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-buten-1-amine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1350716-17-4 (R)-N-[(S)-1-phenylethyl]-2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,2,3,6-tetrahydropyridine 
• 1350716-18-5 (R)-N-[(S)-1-phenylethyl]-2-[(S)-1,2-dihydroxyethyl]-1,2,3,6-tetrahydropyridine 
• 1350716-19-6 (R)-N-[(S)-1-phenylethyl]-2-[(S)-oxiran-2-yl]-1,2,3,6-tetrahydropyridine 
• 203056-17-1 (R)-1-[N-(tert-butyloxycarbonyl)piperidin-2-yl]-1-phenylethene 

Relevant academic research and scientific papers

Concise and facile synthesis of (R,R)-dexmethylphenidate hydrochloride and its three stereoisomers

A new and concise route is reported for the first time for the preparation of four stereoisomers of dexmethylphenidate hydrochloride starting from a single reactant, 2-benzyolpyridine, through an eight-step reaction process, which includes hydrogenation,

Switch in regioselectivity of epoxide ring-opening by changing the organometallic reagent

The regio- and stereoselective ring-opening of a 2-(2′-oxiranyl)-1,2, 3,6-tetrahydropyridine using organometallic reagents is reported. The choice of the organometallic reagent determines the formation of either 2-[(R)-1-hydroxyalkyl]- or 2-[(S)-2-hydroxy

Asymmetric synthesis and pharmacology of methylphenidate and its para- substituted derivatives

We report the first asymmetric synthesis of the individual enantiomers of methylphenidate (1). From d-pipecolic acid, the (2R,2'R) and (2S,2'R) enantiomers of 1 were obtained in >99% optical purity while the (2S,2'S) and (2R,2'S) enantiomers of 1 were der