203062-02-6Relevant articles and documents
Synthesis of3H-, 13C3-, and 14C-labeled Sch 727965
Lavey, C. Flader,Hesk,Koharski,Truong,McNamara
, p. 196 - 201 (2011)
The preparation of [3H]Sch 727965 from unlabeled compound and tritiated water was base catalyzed. Diethyl [13C3]malonate was used to prepare [13C3]Sch 727965 in five steps in 21.8% overall yield. In a similar manner, [14C]Sch 727965 was prepared in five steps from diethyl [2-14C]malonate in 11.1% radiochemical yield. Copyright
Synthesis of 3-amino-4-substituted pyrazole derivatives
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Page/Page column 7, (2010/11/25)
This application discloses a novel process to synthesize 3-amino-4-substituted pyrazole derivatives, which may be used, for example, as intermediates to prepare compounds having, for example, pharmaceutical utility.
PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS
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Page 30, (2008/06/13)
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.