203116-01-2

Upstream product

• 99-96-7 4-hydroxy-benzoic acid 
• 40782-54-5 4-heptyloxybenzoyl chloride 
• 629-04-9 1-Bromoheptane 
• 619-57-8 p-hydroxybenzamide 
• 15872-42-1 4-heptyloxybenzoic acid 

Downstream Products

• 39905-44-7 4-heptyloxyaniline 
• 1033125-88-0 4-(4-Heptyloxy-phenylazo)-phenol 
• 4950-92-9 4-(heptyloxy)benzylamine 
• 1443792-00-4 (S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(2-(4-(heptyloxy)phenyl)thiazol-4-yl)phenyl)propanoate 
• 1443791-99-8 4-(4-bromophenyl)-2-(4-(heptyloxy)phenyl)thiazole 
• 77477-92-0 4-(heptyloxy)benzothioamide 

Relevant academic research and scientific papers

A series of 2, 4, 5-trisubstituted oxazole: Synthesis, characterization and DFT modelling

A new series of 2,4,5-trisubstituted oxazole were synthesized with good yields using simple methodology. All the compounds were thoroughly characterized by IR, NMR (1H and 13C) and mass spectrometry and structures of 2-(4-butyloxyphenyl)-4,5-dimethyloxazole (5b) and 4,5-dimethyl-2-(4-(octyloxy)phenyl)oxazole(5e) were unambiguously determined by X-ray crystallography. Evidently, the crystal structures of these compounds showed C-HaN and C-HaO intermolecular interactions. The electronic structures of these compounds were also studied by DFT at B3LYP/6-311G ++ level of theory.

Photoresponsive behavior of hydrophilic/hydrophobic-based novel azobenzene mesogens: Synthesis, characterization and their application in optical storage devices

Three series of alkoxy chain-bearing azobenzene-derived quaternary ammonium iodides with an alkoxy chain at one end, namely N,N-diethanol-6-(4-((4′-alkyloxyphenyl)diazenyl)phenoxy)hexan-1-ammonium iodides, N-ethyl-N-ethanol-6-(4-((4′-alkyloxyphenyl)diazenyl)phenoxy)hexan-1-ammonium iodides and N,N-diethyl-6-(4-((4′-alkyloxyphenyl)diazenyl)phenoxy)hexan-1-ammonium iodides were synthesized and characterized. Their mesomorphic and photoswitching properties were examined via polarising optical microscopy (POM), differential scanning calorimetry (DSC) and UV-vis spectrophotometry. The liquid crystalline tilted schlieren texture of smectic C, non-tilted natural focal conic texture of smectic A and smectic B phases were observed in the N,N-diethanol- and N-ethyl-N-ethanol-bearing ammonium group substituted at the terminal via the alkoxy chain of the azo moiety. In these azo moieties, the equilibrium time for trans-cis isomerization was about 1 min and cis-trans isomerization occurred at around 590 min, which had the highest alkoxy chain and no hydroxyl group on their head group. The absence of a hydroxyl group on the terminal head group resulted in slow thermal back relaxation, whereas the hydroxyl group-bearing head group showed fast thermal back relaxation. These results suggest that the influence of the substituent on the cationic ammonium head group and alkoxy chain length on the photoisomerization of the azo compounds is vital for optical storage devices. Furthermore, the device fabricated using these materials demonstrated that they are excellent candidates for optical image storage applications.

2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia

This invention provides compounds of Formula I having the structure wherein:B, C, D, and R1 are as defined hereinbefore in the specification, or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.