203173-70-0Relevant articles and documents
Semisynthesis of DB-67 and other silatecans from camptothecin by thiol-promoted addition of silyl radicals
Du, Wu,Kaskar, Bashir,Blumbergs, Peter,Subramanian,Curran, Dennis P.
, p. 451 - 458 (2007/10/03)
Thiol- or acid-promoted additions of silyl radicals to camptothecin are reported. At 105°C, mixtures of 7-silyl (favored) and 12-silyl camptothecins are formed alongside substantial amounts of recovered camptothecin. At 160°C, 12-silyl isomers are formed