203186-01-0 Usage
General Description
(4-Bromophenyl)[1-(trifluoroacetyl)-4-piperidinyl]methanone is a chemical compound with the molecular formula C16H14BrF3NO2. It is a piperidinyl ketone derivative with a trifluoroacetyl group and a bromophenyl group attached to the piperidine ring. (4-BROMOPHENYL)[1-(TRIFLUOROACETYL)-4-PIPERIDINYL]METHANONE has potential use as a building block in the synthesis of pharmaceuticals and other organic compounds. It may also have applications in research as a reagent or intermediate in chemical reactions. Additionally, its structural features make it a potentially interesting compound for studying its pharmacological and biological properties. However, further research is needed to fully understand its potential uses and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 203186-01-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,3,1,8 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 203186-01:
(8*2)+(7*0)+(6*3)+(5*1)+(4*8)+(3*6)+(2*0)+(1*1)=90
90 % 10 = 0
So 203186-01-0 is a valid CAS Registry Number.
203186-01-0Relevant articles and documents
PIPERIDINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS
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Page/Page column 30, (2010/02/12)
Pharmaceutical compositions for the treatment of HIV are provided comprising compounds of formula (II) or a pharmaceutically acceptable salt or isomer thereof, in combination with specified antiviral agents.
Discovery of 4-[(Z)-(4-bromophenyl)(ethoxyimino)methyl]-1′-[(2,4-dimethyl- 3pyridinyl)carbonyl]-4′-methyl-1,4′bipiperidine N-oxide (SCH 351125): An orally bioavailable human CCR5 antagonist for the treatment of HIV infection
Palani,Shapiro,Clader,Greenlee,Cox,Strizki,Endres,Baroudy
, p. 3339 - 3342 (2007/10/03)
Structure - activity studies on piperidino-piperidine 3 led to the discovery of SCH 351125 (1), a selective CCR5 antagonist with potent activity against RANTES binding (Ki=2 nM), which possesses subnanomolar activity in blocking viral entry and
