203187-56-8

Basic information

• Product Name: ETHYL 3-HYDROXY-4-IODOBENZOATE
• Synonyms: ETHYL 3-HYDROXY-4-IODOBENZOATE;RARECHEM AL BI 0964;ETHYL 4-IODO 3-HYDROXY BENZOATE
• CAS NO: 203187-56-8
• Molecular Formula: C₉H₉IO₃
• Molecular Weight: 292.07
• Mol File: 203187-56-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 119-120 °C
• Boiling Point: 313.606 °C at 760 mmHg
• Flash Point: 143.464 °C
• Appearance: /
• Density: 1.777 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.616
• PKA: 7.75±0.10(Predicted)
• CAS DataBase Reference: ETHYL 3-HYDROXY-4-IODOBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-HYDROXY-4-IODOBENZOATE(203187-56-8)
• EPA Substance Registry System: ETHYL 3-HYDROXY-4-IODOBENZOATE(203187-56-8)

Safety Data

• Hazardous Substances Data: 203187-56-8(Hazardous Substances Data)

Usage

General Description

ETHYL 3-HYDROXY-4-IODOBENZOATE is a chemical compound with the molecular formula C9H9IO3. It is a derivative of benzoic acid and is commonly used in organic synthesis and pharmaceutical research. It is a white to off-white crystalline solid that is slightly soluble in water but soluble in organic solvents. ETHYL 3-HYDROXY-4-IODOBENZOATE is known for its potential use as a building block in the synthesis of various pharmaceutical compounds and as an intermediate in the production of agrochemicals. It is important to handle this compound with care and to follow proper safety procedures, as it can be hazardous if not handled properly.

InChI:InChI=1/C9H9IO3/c1-2-13-9(12)6-3-4-7(10)8(11)5-6/h3-5,11H,2H2,1H3

Upstream product

• 64-17-5 ethanol 
• 58123-77-6 3-hydroxy-4-iodobenzoic acid 
• 7781-98-8 ethyl-3-hydroxybenzoate 

Downstream Products

• 741699-04-7 3-ethoxy-4-iodo-benzoic acid ethyl ester 
• 1425822-37-2 (S)-ethyl 4-[8-amino-1,2,4,5-tetrahydro-2-(2-methylpropyl)-4-(3-methylbutyl)-3-oxo-3H-1,4-benzodiazepin-7-yl]-3-[2-(benzyloxy)ethoxy]benzoate 
• 1425822-40-7 C₂₉H₄₁N₃O₅ 
• 1429230-67-0 C₂₄H₃₁BO₆ 
• 1425822-34-9 ethyl 3-[2-(benzyloxy)ethoxy]-4-iodobenzoate 
• 1459128-87-0 ethyl 3-(2-ethoxy-2-oxoethoxy)-4-iodobenzoate 
• 1258071-57-6 ethyl 2-phenylbenzofuran-6-carboxylate 

Relevant articles and documents

MACROCYCLIC COMPOUND AND USE THEREOF

A compound represented by the following formula (I): wherein each symbol in the formula is as described herein or a salt thereof has an NRF2 activating activity, and is expected to be useful as a preventive or therapeutic agent for diseases associated with oxidative stress, in particular, hepatic disease (for example, non-alcoholic steatohepatitis (NASH)), cardiovascular disease (for example, heart failure or pulmonary arterial hypertension), lung disease (for example, chronic obstructive pulmonary disease (COPD)), kidney disease (for example, chronic kidney disease (CKD) or acute kidney injury (AKI)), central nervous system disease (for example, Parkinson's disease), mitochondrial disease (for example, Friedreich motor ataxia, mitochondrial myopathy), inflammatory disease (for example, multiple sclerosis (MS), inflammatory bowel disease (IBD)), sickle cell disease, cancer, or the like.

AMPA RECEPTOR POTENTIATORS

The present invention relates to AMPA receptor potentiators of Formula I: formulations comprising them, methods for their use, and intermediates useful for their preparation.

ARYL PIPERIDINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA

This invention relates to novel compounds which up-regulate LDL receptor (LDL-r) expression and to processes for their preparation, pharmaceutical compositions containing them and their medical use. More particularly, this invention relates to novel aromatic piperidines of formula (I) and their use in therapy.