2032-48-6

Basic information

• Product Name: (6Z)-6-[piperidin-1-yl(sulfanyl)methylidene]cyclohexa-2,4-dien-1-one
• CAS NO: 2032-48-6
• Molecular Formula: C₁₂H₁₅NOS
• Molecular Weight: 221.3186
• Mol File: 2032-48-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 341.4°C at 760 mmHg
• Flash Point: 160.3°C
• Density: 1.212g/cm³
• Vapor Pressure: 8.08E-05mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: (6Z)-6-[piperidin-1-yl(sulfanyl)methylidene]cyclohexa-2,4-dien-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (6Z)-6-[piperidin-1-yl(sulfanyl)methylidene]cyclohexa-2,4-dien-1-one(2032-48-6)
• EPA Substance Registry System: (6Z)-6-[piperidin-1-yl(sulfanyl)methylidene]cyclohexa-2,4-dien-1-one(2032-48-6)

Safety Data

• Hazardous Substances Data: 2032-48-6(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 90-02-8 salicylaldehyde 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 2032-49-7 1-(2-hydroxy-thiobenzoyl)-1-methyl-piperidinium; iodide 
• 77951-58-7 α-<<(2-Hydroxyphenyl)thiocarbonyl>thio>phenylessigsaeure 
• 76226-62-5 o-benzenecarboxythiobenzopiperide 
• 1451837-14-1 C₁₉H₂₀N₄O₄S₂ 
• 57598-98-8 carboxymethyl o-hydroxydithiobenzoate 
• 77951-64-5 2-phenyl-4H-thieno<3,2-c><1>benzopyran 
• 77951-59-8 5-Phenyl-2-<2-(trifluoracetoxy)phenyl>-1,3-dithiolylium-4-olat 
• 77951-62-3 5-Phenyl-2-<2-(propargyloxy)phenyl>-1,3-dithiolylium-4-olat 
• 77951-61-2 2-<2-(Allyloxy)phenyl>-5-phenyl-1,3-dithiolylium-4-olat 
• 77951-63-4 3,4,t-4a,5-Tetrahydro-3-phenyl-r-3,c-10b-epithio-2H,10bH-thiino<3,2-c>benzopyran-2-on 
• 77951-60-1 2-(2-Hydroxyphenyl)-5-phenyl-1,3-dithiolylium-4-olat 
• 111997-47-8 2-(o-Hydroxy-α-piperidinobenzylidene)salicylohydrazide 
• 112020-92-5 2-(2-hydroxyphenyl)-5-(4-pyridyl)-1,3,4-oxadiazole 
• 18233-24-4 2-(5-phenyl-1,3,4-oxadiazol-2-yl)phenol 

Relevant articles and documents

Syntheses and antitumor activities of N′1, N′3-dialkyl-N′1,N′3-di- (alkylcarbonothioyl) malonohydrazide: The discovery of elesclomol

A series of N′1,N′3-dialkyl- N′1,N′3-di(alkylcarbonothioyl) malonohydrazides have been designed and synthesized as anticancer agents by targeting oxidative stress and Hsp70 induction. Structure-activity relationship (SAR) studies lead to the discovery of STA-4783 (elesclomol), a novel small molecule that has been evaluated in a number of clinical trials as an anticancer agent in combination with Taxol.

Examinations of thioamides and their derivatives. X. Salts 1-(o-hydroxy)-alpha-alkylthiobenzylidene) piperidinium, structure, properties and biological activity

In reactions of 1-(o-hydroxy)thiobenzoylpiperidine with alkyl halides there was obtained 1-(o-hydroxy-alpha-alkylthiobenzylidene)piperidinium bromides and iodides. Structure of obtained compounds have been determined by spectroscopic methods. Products of hydrolysis their and antimitotic and enzymatic activity were investigated too.