203245-06-1

Basic information

• Product Name: N-but-3-enyl-2,2-dichloro-N-cyclohex-1-enyl-acetamide
• CAS NO: 203245-06-1
• Molecular Weight: 262.179
• Mol File: 203245-06-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-but-3-enyl-2,2-dichloro-N-cyclohex-1-enyl-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-but-3-enyl-2,2-dichloro-N-cyclohex-1-enyl-acetamide(203245-06-1)
• EPA Substance Registry System: N-but-3-enyl-2,2-dichloro-N-cyclohex-1-enyl-acetamide(203245-06-1)

Safety Data

• Hazardous Substances Data: 203245-06-1(Hazardous Substances Data)

Upstream product

• 203245-04-9 N-but-3-enyl-2,2,2-trichloro-N-cyclohex-1-enyl-acetamide 
• 108-94-1 cyclohexanone 
• 144809-24-5 But-3-enyl-cyclohexylidene-amine 

Relevant articles and documents

β- and γ-lactams by nickel powder mediated 4-exo or 5-endo radical cyclisations. A concise construction of the mesembrine skeleton

N-Alkenyl trichloroacetamides, upon treatment with nickel powder and acetic acid in refluxing 2-propanol undergo reversible 4-exo radical cyclisation. The cyclised radical can be trapped in different ways leading to β-lactams. When the trap is omitted or not efficient enough, unusual irreversible 5-endo cyclisation occurs affording functionalised five-membered lactams. Synthesis of bicyclic γ-lactams has also been examined providing in few steps an access to the Sceletium alkaloids skeleton.