203259-90-9Relevant articles and documents
Engineered P450pyr monooxygenase for asymmetric epoxidation of alkenes with unique and high enantioselectivity
Li, Aitao,Liu, Ji,Pham, Son Q.,Li, Zhi
supporting information, p. 11572 - 11574 (2013/12/04)
A triple mutant of P450pyr monooxygenase (P450pyrTM) catalysed the epoxidation of several para-substituted styrenes as the first enzyme showing high (R)-enantioselectivity and high conversion, demonstrated a broad substrate range, and showed high enantioselectivity for the epoxidation of an unconjugated 1,1-disubstituted alkene, 2-methyl-3-phenyl-1-propene, and a cyclic alkene, N-phenoxycarbonyl-1,2,5,6-tetrahydropyridine, respectively.