203302-92-5 Usage
Uses
Used in Chemical Synthesis:
3-Bromo-2-chloro-6-fluorotoluene is used as a chemical intermediate for the synthesis of various complex organic compounds. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable component in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Research Applications:
In the field of scientific research, 3-bromo-2-chloro-6-fluorotoluene is employed as a model compound for studying the effects of halogen substitution on the reactivity and properties of toluene derivatives. This helps researchers understand the fundamental principles governing the behavior of such compounds and can lead to the development of new synthetic methods and applications.
Used in Material Science:
3-Bromo-2-chloro-6-fluorotoluene is used as a precursor in the development of novel materials with specific properties, such as high thermal stability or unique electronic characteristics. Its incorporation into polymers or other materials can lead to the creation of advanced materials for use in various industries, including electronics, aerospace, and automotive.
Check Digit Verification of cas no
The CAS Registry Mumber 203302-92-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,3,3,0 and 2 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 203302-92:
(8*2)+(7*0)+(6*3)+(5*3)+(4*0)+(3*2)+(2*9)+(1*2)=75
75 % 10 = 5
So 203302-92-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BrClF/c1-4-6(10)3-2-5(8)7(4)9/h2-3H,1H3
203302-92-5Relevant academic research and scientific papers
Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators
Schlienger, Nathalie,Lund, Birgitte W.,Pawlas, Jan,Badalassi, Fabrizio,Bertozzi, Fabio,Lewinsky, Rasmus,Fejzic, Alma,Thygesen, Mikkel B.,Tabatabaei, Ali,Bradley, Stefania Risso,Gardell, Luis R.,Piu, Fabrice,Olsson, Roger
supporting information; experimental part, p. 7186 - 7191 (2010/07/04)
Herein we describe the discovery of ACP-105 (1), a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone. Compound 1 was developed from a series of compounds found in a HTS screen using the receptor selection and amplification technology (R-SAT). In vivo, 1 improved anabolic parameters in a 2-week chronic study in castrated male rats. In addition to compound 1, a number of potent antiandrogens were discovered from the same series of compounds whereof one compound, 13, had antagonist activity at the AR T877A mutant involved in prostate cancer.
Aminophenyl derivatives as selective androgen receptor modulators
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Page/Page column 18, (2008/06/13)
Disclosed herein is a novel class of aminophenyl compounds having the structure: wherein R1 is cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or preventi