203318-14-3Relevant academic research and scientific papers
Total synthesis of sollasin a and sollasin d via photocycloaddition of methyl 2,4-dioxopentanoate to methyl E-2-methyl-2-butenoate
Hatsui, Toshihide,Taga, Masashi,Mori, Akira,Takeshita, Hitoshi
, p. 113 - 114 (1998)
Starting from photocycloaddition of methyl 2,4-dioxopentanoate to methyl tiglate, an electron-deficient olefin, methyl-migrated monocyclofarnesyl sesquiterpenoids, d,l-sollasin a and d, antibacterial compounds, were synthesized.
Total Synthesis and Structure Revision of Halioxepine
Poock, Caroline,Kalesse, Markus
supporting information, p. 1615 - 1619 (2020/12/23)
The first total synthesis of halioxepine is accomplished using a 1,4-addition for constructing the quaternary center at C10 and a halo etherification for the generation of the tertiary ether at C7. The correct structure of halioxepine was determined by assembling different enantiomeric building blocks and by changing the relative configuration between C10 and C15.
