2034-25-5 Usage
Properties
1. Role: Intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes
2. Reagent: Commonly used in organic synthesis
3. Applications:
Organic Synthesis: Especially in the preparation of heterocyclic compounds and pharmaceuticals
Herbicides and Fungicides: Building block in their synthesis
Anti-tumor Potential: Subject of research for its pharmacological properties
4. Versatility: Wide range of applications in various industries
Check Digit Verification of cas no
The CAS Registry Mumber 2034-25-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,3 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2034-25:
(6*2)+(5*0)+(4*3)+(3*4)+(2*2)+(1*5)=45
45 % 10 = 5
So 2034-25-5 is a valid CAS Registry Number.
2034-25-5Relevant articles and documents
Karachanov et al.
, (1969)
Triazole derivatives: A series of Darapladib analogues as orally active Lp-PLA2 inhibitors
Wang, Kai,Xu, Wenwei,Zhang, Wei,Mo, Mingguang,Wang, Yiping,Shen, Jianhua
, p. 2897 - 2901 (2013/06/26)
This Letter reports our efforts towards the optimization of our previously identified series of imidazole and triazole derivatives that lead to the discovery of a series of orally active Lp-PLA2 inhibitors in C57 mice. These inhibitors are characterized by the presence of a diamine side chain in the molecules, such as 2c, 2f, and 4a. The introduction of the terminal-end amine succeeded in maintaining the in vitro activities at sub-nanomolar levels. The vivo activities could be greatly affected by variations in the two amines via modulating the metabolic stability and lipophilicity of the compounds.
