203437-89-2Relevant academic research and scientific papers
Reactions of β-ethylsulfanylpropionyl tetrafluoroborate with electron-rich aromatics: A novel synthesis of aryl vinyl ketones
Lebedev, Mikhail V.,Nenajdenko, Valentine G.,Balenkova, Elizabeth S.
, p. 89 - 93 (1998)
A new synthesis of aryl vinyl ketones is described. The acylation of active aromatics with the complex of β-ethylsulfanylpropionyl fluoride 1 and boron trifluoride leads to formation of 1-aryl-3-(ethylsulfanyl)propan-1-ones. Subsequent methylation with methyl triflate and elimination with an aqueous solution of KHCO3 results in formation of aryl vinyl ketones in 86-99% yield.
