203449-67-6Relevant academic research and scientific papers
Stereocontrolled approach to highly substituted cyclopentanones. Application in a formal synthesis of Δ(9(12))-capnellene
Samajdar, Susanta,Patra, Debasis,Ghosh, Subrata
, p. 1789 - 1800 (2007/10/03)
A direct stereocontrolled route for the construction of highly substituted cyclopentanones 10a-d has been developed starting from acyclic ketones 5a,b. The key step involves copper(I)-catalysed stereoselective photocycloaddition of the dienes 6a-d followed by stereospecific rearrangement of the cyclobutane derivatives 7a,b, 8 and 9. Employing this methodology a formal synthesis of the sesquiterpene Δ(9(12))-capnellene 2 has been achieved.
Intramolecular [2 + 2]photocycloaddition-cyclobutane rearrangement. A novel stereocontrolled approach to highly substituted cyclopentanones
Ghosh,Patra,Samajdar
, p. 2073 - 2076 (2007/10/03)
A simple stereocontrolled route involving intramolecular [2 + 2] photocycloaddition followed by rearrangement of the resulting cyclobutane derivatives is described for the construction of cyclopentanones with substituents upto three contiguous chiral centres.
