203510-09-2

Basic information

• Product Name: 2-Piperidinone, 1-(2-methyl-4-nitrophenyl)-
• CAS NO: 203510-09-2
• Molecular Formula: C12H14N2O3
• Molecular Weight: 234.255
• Mol File: 203510-09-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Piperidinone, 1-(2-methyl-4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinone, 1-(2-methyl-4-nitrophenyl)-(203510-09-2)
• EPA Substance Registry System: 2-Piperidinone, 1-(2-methyl-4-nitrophenyl)-(203510-09-2)

Safety Data

• Hazardous Substances Data: 203510-09-2(Hazardous Substances Data)

Upstream product

• 51248-16-9 1-(2-methyl-4-nitro-phenyl)-piperidine 
• 675-20-7 piperidin-2-one 
• 7149-70-4 2-bromo-5-nitrotoluene 
• 1575-61-7 5-Chlorovaleroyl chloride 
• 99-52-5 2-methyl-4-nitro-benzenamine 

Relevant articles and documents

Multiple crystal forms of pyridine derivative, and preparation methods and application thereof

The invention specifically relates to multiple crystal forms of a compound, i.e., 1-(4-methoxyphenyl)-7-oxo-6-[2-methyl-4(2-oxotetrahydropyrrol-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide, and preparation methods thereof, and application of the multiple crystal forms to preparation of drugs used for preventing or treating thrombosis or embolism, belonging to the field of chemical synthesis of drugs.

PROLINE DERIVATIVES

The invention relates to novel compounds of formula (I), wherein X, Y, R1, R2, R3, R4 and n have the meaning cited in claim 1, are inhibitors of the coagulation factor Xa and can be used for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.

The reactivity of nitrophenyl substituted cyclic amines with dehydrogenations

Piperidine and perhydroazepine bearing a 1-(4-nitrophenyl) substituent were inert to mercury-edta, while the α-pipecoline derivative gave an aminoketone with cleavage of the heterocycle. However the corresponding (2-nitrophenyl) compounds reacted to give