203510-25-2Relevant academic research and scientific papers
ENZYMATIC KINETIC RESOLUTION OF CYANOHYDRIN ACETATES AND ITS APPLICATION TO THE SYNTHESIS OF (S)-(-)-FRONTALIN
Ohta, Hiromichi,Kimura, Yoichi,Sugano, Yasushi,Sugai, Takeshi
, p. 5469 - 5476 (2007/10/02)
Kinetic resolution of racemic 1-cyano-1-methylalkyl and alkenyl acetates has been achieved on incubation with Pichia miso IAM 4682, which hydrolyzed selectively the (R)-enantiomer, leving behind the (S)-enantiomer intact.The chiral 1-cyano-1-methyl-5-hexenyl acetate thus obtained was converted to (S)-frontalin via unsaturated diol.
