203516-80-7Relevant academic research and scientific papers
An efficient synthetic strategy for the preparation of 2,3,6,7-tetrahydro-3-phenyl-4H-oxazolo[3,2-a]-1,3,5-triazin-2,4-diones
Forfar,Bosc,Leger,Jarry
, p. 9 - 12 (2007/10/03)
An efficient synthesis of 2,3,6,7-tetrahydro-3-phenyl-4H-oxazolo[3,2-a]-1,3,5-triazin-2,4-diones (4) is described. 2-Amino-2-oxazolines (1) were treated with electrophilic compounds to form, in two steps, 3-carboethoxy-2-phenylcarbamoyl-2-iminooxazolidines (3). These products were cyclized at high temperature in the presence of two equivalents of phenyl isocyanate. The structure of the 2,3,6,7-tetrahydro-3-phenyl-7-methoxymethyl-4H-oxazolo[3,2-a]-1,3,5-triazin-2,4 -dione (4a) was confirmed by X-ray crystallography.
