203520-15-4

Upstream product

• 203520-14-3 13-(tert-Butyldimethylsilanyloxy)-16-(tert-butyldiphenylsilanyloxy)-3,7-dimethoxy-5-methoxymethoxy-4,8,12,14-tetramethyl-11-oxohexadecanal 
• 301230-11-5 4-Benzyl-3-{5-benzyloxy-2-[5-(tert-butyldiphenylsilanyloxy)-1-hydroxy-3-methoxy-4-methylpentyl]pent-3-enoyl}oxazolidin-2-one 
• 301230-12-6 2-(3-Benzyloxyprop-1-enyl)-7-(tert-butyldiphenylsilanyloxy)-5-methoxy-6-methylheptane-1,3-diol 
• 166322-53-8 tert-Butyl(3,7,9,9-tetramethoxy-5-methoxymethoxy-2,6-dimethylnonyloxy)diphenylsilane 
• 166322-59-4 [4,6-Bis(tert-butyldimethylsilanyloxy)-3,5-dimethylhexyloxymethyl]benzene 
• 166322-54-9 3,7,9,9-Tetramethoxy-5-methoxomethoxy-2,6-dimethylnonan-1-ol 
• 166322-56-1 Ethyl 6-benzyloxy-4-methylhex-2-enoate 
• 166322-48-1 6-(tert-Butyldimethylsilanyloxy)-10-(tert-butyldiphenylsilanyloxy)-8-methoxy-5,9-dimethyldec-1-en-4-ol 
• 203520-13-2 4-(tert-Butyldimethylsilanyloxy)-1-(tert-butyldiphenylsilanyloxy)-10,14,16,16-tetramethoxy-12-methoxymethoxy-3,5,9,13-tetramethylhexadec-6-one 
• 166322-64-1 1-Benzyloxy-4-(tert-butyldimethylsilanyloxy)-10,14,16,16-tetramethoxy-12-methoxymethoxy-3,5,9,13-tetramethylhexadec-7-en-6-one 
• 301230-15-9 1-Benzyloxy-9-(tert-butyldiphenylsilanyloxy)-7-methoxy-4,8-dimethylnon-2-en-5-yl tert-butyldimethylsilyl ether 
• 166322-49-2 6-(tert-Butyldimethylsilanyloxy)-10-(tert-butyldiphenylsilanyloxy)-4,8-dimethoxy-5,9-dimethyldec-1-ene 
• 166322-47-0 3-(tert-Butyldimethylsilanyloxy)-7-(tert-butyldiphenylsilanyloxy)-5-methoxy-2,6-dimethylheptanal 
• 166322-51-6 tert-Butyl(3,7-dimethoxy-5-methoxomethoxy-2,6-dimethyldec-9-enyloxy)diphenylsilane 

Downstream Products

• 203520-17-6 (E)-(3R,4R,5S,9S,10R,12R,13S,14R)-4-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-diphenyl-silanyloxy)-17-(4-hydroxymethyl-[2,4';2',4'']teroxazol-2''-yl)-10,14-dimethoxy-12-methoxymethoxy-3,5,9,13-tetramethyl-heptadec-16-en-6-ol 
• 203520-18-7 2''-[(E)-(4R,5S,6R,8R,9S,13R,14R,15R)-14-(tert-Butyl-dimethyl-silanyloxy)-17-(tert-butyl-diphenyl-silanyloxy)-4,8-dimethoxy-6-methoxymethoxy-5,9,13,15-tetramethyl-12-oxo-heptadec-1-enyl]-[2,4';2',4'']teroxazole-4-carbaldehyde 
• 203520-19-8 2''-[(E)-(4R,5R,6R,8R,9S,13R,14R,15R)-14-(tert-Butyl-dimethyl-silanyloxy)-17-(tert-butyl-diphenyl-silanyloxy)-6-hydroxy-4,8-dimethoxy-5,9,13,15-tetramethyl-12-oxo-heptadec-1-enyl]-[2,4';2',4'']teroxazole-4-carbaldehyde 

Relevant academic research and scientific papers

A total synthesis of the unique tris-oxazole macrolide ulapualide a produced by the marine nudibranch Hexabranchus sanguineus

A total synthesis of ulapualide A (1), whose relative stereochemistry was assigned on the basis of an earlier molecular mechanics study of its hypothetical metal chelated complex 9, is described. The synthesis is based on: i, elaboration of the double fun

Towards a total synthesis of ulapualide A. A concise synthesis of the tris-Oxazole macrolide core and entire carbon skeleton

A concise synthesis of the tris-oxazole based macrocyclic core viz 14 of ulapualide A 1, incorporating all the correct stereogenic centres at C-3 and along the C25-C40 portion of the natural product, is described.