203572-17-2

Upstream product

• 203572-13-8 (5S,6S)-5,6-Dihydroxy-oct-7-enoic acid ethyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 6630-33-7 ortho-bromobenzaldehyde 
• 203572-15-0 (5S,6S)-5,6-Bis-(tert-butyl-dimethyl-silanyloxy)-oct-7-enoic acid ethyl ester 

Downstream Products

• 203572-30-9 (E)-(5S,6S)-5,6-Bis-(tert-butyl-dimethyl-silanyloxy)-8-[2-((E)-3-hydroxy-oct-1-enyl)-phenyl]-oct-7-enoic acid ethyl ester 

Relevant academic research and scientific papers

Palladium-catalyzed Coupling Reactions of Bromobenzaldehydes with 3,4-Di(tert-butylmethylsilyloxy)-1-alkene to (3,4-Dihydroxyalkenyl)benzaldehydes in the Synthesis of Lipoxin Analogues

o-, m-, and p-(3,4-Dihydroxyalkenyl)benzaldehydes were selectively prepared via palladium-catalyzed Heck-type coupling reactions of o-, m-, and p-bromobenzaldehydes with 3,4-di(tert-butyldimethylsilyloxy)-1-alkene.The products were employed for the synthesis of lipoxin analogues, o-, m-, and p-3-hydroxyalkenyl-3,4-dihydroxyalkenylbenzenes.